Detalhe da pesquisa
1.
LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.
BMC Cancer
; 24(1): 147, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38291372
2.
Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.
Lancet Oncol
; 20(7): 1011-1022, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31151904
3.
A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas.
Pediatr Blood Cancer
; 65(2)2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29090526
4.
A phase 1/2 dose-finding, safety, and activity study of cabazitaxel in pediatric patients with refractory solid tumors including tumors of the central nervous system.
Pediatr Blood Cancer
; 65(9): e27217, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29750396
5.
ONC201 (Dordaviprone) in Recurrent H3 K27M-Mutant Diffuse Midline Glioma.
J Clin Oncol
; 42(13): 1542-1552, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38335473
6.
The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
Nat Med
; 30(1): 207-217, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37978284
7.
Long-term efficacy and toxicity of bevacizumab-based therapy in children with recurrent low-grade gliomas.
Pediatr Blood Cancer
; 60(5): 776-82, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22976922
8.
Phase I/II trial of vorinostat and radiation and maintenance vorinostat in children with diffuse intrinsic pontine glioma: A Children's Oncology Group report.
Neuro Oncol
; 24(4): 655-664, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34347089
9.
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
Neuro Oncol
; 23(10): 1777-1788, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33631016
10.
Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAFV600E-Mutant Human Glioma.
Clin Cancer Res
; 27(22): 6197-6208, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433654
11.
Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report.
Neuro Oncol
; 22(11): 1696-1704, 2020 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393959
12.
Harmonization of postmortem donations for pediatric brain tumors and molecular characterization of diffuse midline gliomas.
Sci Rep
; 10(1): 10954, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32616776
13.
Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
Nat Med
; 30(5): 1500, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467878
14.
Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.
Clin Cancer Res
; 24(23): 5850-5859, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322880
15.
Pediatric low-grade gliomas: implications of the biologic era.
Neuro Oncol
; 19(6): 750-761, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683733
16.
Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study.
Neuro Oncol
; 24(8): 1404, 2022 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35307742
17.
Separation of outer retinal layers secondary to selumetinib.
J AAPOS
; 20(3): 268-71, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27108842
18.
Clinicopathology of diffuse intrinsic pontine glioma and its redefined genomic and epigenomic landscape.
Cancer Genet
; 208(7-8): 367-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26206682
19.
A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study.
Neuro Oncol
; 17(2): 303-11, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25431212
20.
Handheld optical coherence tomography during sedation in young children with optic pathway gliomas.
JAMA Ophthalmol
; 132(3): 265-71, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24435762