Detalhe da pesquisa
1.
Antibody-guided proteases enable selective and catalytic degradation of challenging therapeutic targets.
J Biol Chem
; 299(5): 104685, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031819
2.
Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.
J Biol Chem
; 292(9): 3900-3908, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28077575
3.
Susceptibility of Antibody CDR Residues to Chemical Modifications Can Be Revealed Prior to Antibody Humanization and Aid in the Lead Selection Process.
Mol Pharm
; 15(10): 4529-4537, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118239
4.
Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.
Mol Pharm
; 13(9): 2996-3003, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27244474
5.
A novel, label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells.
Br J Pharmacol
; 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783572
6.
Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening.
Protein Eng Des Sel
; 30(9): 627-637, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985411
7.
Evading pre-existing anti-hinge antibody binding by hinge engineering.
MAbs
; 8(8): 1536-1547, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27606571
8.
Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.
Invest Ophthalmol Vis Sci
; 56(9): 5390-400, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26275136
9.
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/ßKlotho Complex.
EBioMedicine
; 2(7): 730-43, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26288846
10.
Translation levels control multi-spanning membrane protein expression.
PLoS One
; 7(4): e35844, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563408
11.
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1.
Sci Transl Med
; 3(113): 113ra126, 2011 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22174314
12.
Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods.
J Immunol
; 176(4): 2069-73, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16455961
13.
Isolation and characterization of the B-cell marker CD20.
Biochemistry
; 44(46): 15150-8, 2005 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16285718
14.
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome Res
; 13(10): 2265-70, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12975309