Detalhe da pesquisa
1.
Common dihydropyrimidinase ( DPYS ) genetic variations do not predict fluoropyrimidine-related chemotherapy toxicity in a Canadian cohort.
Pharmacogenet Genomics
; 34(3): 83-87, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215018
2.
Impact of organic anion transporting polypeptide, P-glycoprotein, and breast cancer resistance protein transporters on observed tamoxifen and endoxifen concentration and adverse effects.
Pharmacogenet Genomics
; 33(1): 10-18, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36373739
3.
Genetic Variation in miR-27a Is Associated with Fluoropyrimidine-Associated Toxicity in Patients with Dihydropyrimidine Dehydrogenase Variants after Genotype-Guided Dose Reduction.
Int J Mol Sci
; 24(17)2023 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686089
4.
In-vitro characterization of coding variants with predicted functional implications in the efflux transporter multidrug resistance protein 4 (MRP4, ABCC4).
Pharmacogenet Genomics
; 32(3): 111-116, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34693929
5.
Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C.
Liver Int
; 42(4): 796-808, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35107877
6.
Implementation of pharmacogenomics: Where are we now?
Br J Clin Pharmacol
; 2022 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36366858
7.
A Comparative Analysis of Drug Therapy, Disease Phenotype, and Health Care Outcomes for Men and Women with Inflammatory Bowel Disease.
Dig Dis Sci
; 67(9): 4287-4294, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34313923
8.
High infliximab trough concentrations are associated with sustained histologic remission in inflammatory bowel disease: a prospective cohort study.
BMC Gastroenterol
; 21(1): 77, 2021 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602145
9.
Baclofen has a risk of encephalopathy in older adults receiving dialysis.
Kidney Int
; 98(4): 979-988, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32450156
10.
Genetic and clinical predictors of arthralgia during letrozole or anastrozole therapy in breast cancer patients.
Breast Cancer Res Treat
; 183(2): 365-372, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32632513
11.
In Vitro Functional Characterization and in Silico Prediction of Rare Genetic Variation in the Bile Acid and Drug Transporter, Na+-Taurocholate Cotransporting Polypeptide (NTCP, SLC10A1).
Mol Pharm
; 17(4): 1170-1181, 2020 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101444
12.
Drug interactions and pharmacogenetic factors contribute to variation in apixaban concentration in atrial fibrillation patients in routine care.
J Thromb Thrombolysis
; 49(2): 294-303, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564018
13.
HLADQA1∗05G>A Genetic Screening Promotes the Safe Delivery of Combination Therapy in Inflammatory Bowel Disease.
Clin Gastroenterol Hepatol
; 22(4): 890-892.e2, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37730155
14.
Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1.
Drug Metab Dispos
; 47(8): 832-842, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31123035
15.
Crohn's Disease Is Associated with Decreased CYP3A4 and P-Glycoprotein Protein Expression.
Mol Pharm
; 16(9): 4059-4064, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31393129
16.
Failure to Achieve Target Drug Concentrations During Induction and Not HLADQA1∗05 Carriage Is Associated With Antidrug Antibody Formation in Patients With Inflammatory Bowel Disease: Is HLADQA1∗05 Gone Before It's Here?
Gastroenterology
; 163(4): 1123-1124, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35427575
17.
CYP2D6 genotype and endoxifen plasma concentration do not predict hot flash severity during tamoxifen therapy.
Breast Cancer Res Treat
; 171(3): 701-708, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29980881
18.
Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer.
Breast Cancer Res Treat
; 172(2): 371-379, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30094551
19.
Apixaban and Rosuvas--tatin Pharmacokinetics in Nonalcoholic Fatty Liver Disease.
Drug Metab Dispos
; 46(5): 485-492, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472495
20.
Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.
Mol Pharmacol
; 91(1): 14-24, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27777271