Detalhe da pesquisa
1.
Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34234012
2.
Published anti-SARS-CoV-2 in vitro hits share common mechanisms of action that synergize with antivirals.
Brief Bioinform
; 22(6)2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245241
3.
Novel SARS-CoV-2 entry inhibitors, 2-anilinoquinazolin-4(3H)-one derivatives, show potency as SARS-CoV-2 antivirals in a human ACE2 transgenic mouse model.
J Med Virol
; 95(6): e28863, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310127
4.
Discovery of 2-aminoquinolone acid derivatives as potent inhibitors of SARS-CoV-2.
Bioorg Med Chem Lett
; 85: 129214, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870624
5.
Comparison of Waning Neutralizing Antibody Responses Against the Omicron Variant 6 Months After Natural Severe Acute Respiratory Syndrome Coronavirus 2 Infection (With or Without Subsequent Coronavirus Disease 2019 [COVID-19] Vaccination) Versus 2-Dose COVID-19 Vaccination.
Clin Infect Dis
; 75(12): 2243-2246, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35686300
6.
Lancemaside A from Codonopsis lanceolata: Studies on Antiviral Activity and Mechanism of Action against SARS-CoV-2 and Its Variants of Concern.
Antimicrob Agents Chemother
; 66(12): e0120122, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36374087
7.
Diagnostic performance and clinical feasibility of a novel one-step RT-qPCR assay for simultaneous detection of multiple severe acute respiratory syndrome coronaviruses.
Arch Virol
; 167(3): 871-879, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35137250
8.
Targeting the Receptor-Binding Motif of SARS-CoV-2 with D-Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of Concern.
J Chem Inf Model
; 62(15): 3618-3626, 2022 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35875887
9.
Synthesis and structure-activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2.
Bioorg Chem
; 127: 105985, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809512
10.
Inhibition of ACE2-Spike Interaction by an ACE2 Binder Suppresses SARS-CoV-2 Entry.
Angew Chem Int Ed Engl
; 61(11): e202115695, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35043545
11.
Neutralization of Zika virus by E protein domain III-Specific human monoclonal antibody.
Biochem Biophys Res Commun
; 545: 33-39, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33535104
12.
An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus.
PLoS Pathog
; 15(2): e1007375, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707748
13.
Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells.
J Med Virol
; 93(3): 1403-1408, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32767684
14.
Design, synthesis and biological evaluation of 2-aminoquinazolin-4(3H)-one derivatives as potential SARS-CoV-2 and MERS-CoV treatments.
Bioorg Med Chem Lett
; 39: 127885, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33662537
15.
Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2.
Bioorg Med Chem Lett
; 31: 127667, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33160024
16.
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366720
17.
Identification of 4-anilino-6-aminoquinazoline derivatives as potential MERS-CoV inhibitors.
Bioorg Med Chem Lett
; 30(20): 127472, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781216
18.
Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitors.
Bioorg Med Chem Lett
; 29(23): 126727, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31624041
19.
Generation of a Nebulizable CDR-Modified MERS-CoV Neutralizing Human Antibody.
Int J Mol Sci
; 20(20)2019 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31614869
20.
Cell culture-adaptive mutations of NS5A affect replication of hepatitis C virus differentially depending on the viral genotypes.
J Med Virol
; 89(1): 146-152, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27253731