Detalhe da pesquisa
1.
Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease.
Int J Mol Sci
; 25(8)2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673751
2.
Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate.
Int J Mol Sci
; 24(5)2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902054
3.
Electroneutral Polymer Nanodiscs Enable Interference-Free Probing of Membrane Proteins in a Lipid-Bilayer Environment.
Small
; 18(47): e2202492, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228092
4.
Brothers in arms: proBDNF/BDNF and sAPPα/Aß-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer's disease.
Biol Chem
; 403(1): 43-71, 2022 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619027
5.
The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research.
Biol Chem
; 403(1): 3-26, 2022 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34449171
6.
Artemisinin-treatment in pre-symptomatic APP-PS1 mice increases gephyrin phosphorylation at Ser270: a modification regulating postsynaptic GABAAR density.
Biol Chem
; 403(1): 73-87, 2022 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33878252
7.
Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-ß and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model.
Mol Cell Neurosci
; 113: 103624, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933588
8.
The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif.
Cell Mol Life Sci
; 77(24): 5223-5242, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065241
9.
The amyloid precursor protein affects glyceraldehyde 3-phosphate dehydrogenase levels, organelle localisation and thermal stability.
Mol Biol Rep
; 47(4): 3019-3024, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152789
10.
Copper and zinc ions govern the trans-directed dimerization of APP family members in multiple ways.
J Neurochem
; 151(5): 626-641, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31063592
11.
Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.
Biol Chem
; 400(9): 1181-1189, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31095505
12.
A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites.
Biol Chem
; 400(9): 1191-1203, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31120852
13.
Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.
Cell Mol Life Sci
; 75(2): 301-322, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28799085
14.
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.
J Neurosci
; 37(21): 5345-5365, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450540
15.
Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model.
Am J Pathol
; 186(9): 2279-91, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27423698
16.
Drug development for neurodegenerative diseases.
Biol Chem
; 403(1): 1, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34791859
17.
Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain.
J Neurosci
; 34(33): 11159-72, 2014 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122912
18.
SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.
J Neurochem
; 135(1): 60-75, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26119586
19.
Differential role of APP and APLPs for neuromuscular synaptic morphology and function.
Mol Cell Neurosci
; 61: 201-10, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24998676
20.
A presenilin 1 mutation in the first case of Alzheimer's disease: revisited.
Alzheimers Dement
; 10(6): 869-72, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25130656