Detalhe da pesquisa
1.
The real unmet need: A multifactorial approach for identifying sensitized kidney candidates with low access to transplant.
Clin Transplant
; 37(5): e14946, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36841966
2.
Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study.
J Am Soc Nephrol
; 33(4): 829-838, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35260419
3.
Imlifidase for the treatment of anti-HLA antibody-mediated processes in kidney transplantation.
Am J Transplant
; 22(3): 691-697, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34467625
4.
Outcomes at 3 years posttransplant in imlifidase-desensitized kidney transplant patients.
Am J Transplant
; 21(12): 3907-3918, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34236770
5.
Desensitization using imlifidase and EndoS enables chimerism induction in allosensitized recipient mice.
Am J Transplant
; 20(9): 2356-2365, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32185855
6.
IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation.
N Engl J Med
; 377(5): 442-453, 2017 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28767349
7.
Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS.
Mol Cell Proteomics
; 17(6): 1097-1111, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29511047
8.
The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease.
Kidney Int
; 96(5): 1234-1238, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31563334
9.
Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients.
Am J Transplant
; 18(11): 2752-2762, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29561066
10.
Authors' Reply: Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies!
J Am Soc Nephrol
; 33(10): 1954-1955, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948436
11.
The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation.
J Immunol
; 195(12): 5592-601, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553074
12.
Administration of immunoglobulin G-degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti-ADAMTS13 antibodies in patients with thrombotic thrombocytopenic purpura in clinical remission.
Br J Haematol
; 186(1): 137-140, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30488420
13.
Imlifidase-generated Single-cleaved IgG: Implications for Transplantation.
Transplantation
; 106(7): 1485-1496, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34966107
14.
IgM single antigen bead HLA-assay is affected by imlifidase through the cleavage of IgG but not IgM.
Transpl Immunol
; 68: 101436, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34265468
15.
Imlifidase Desensitization in Crossmatch-positive, Highly Sensitized Kidney Transplant Recipients: Results of an International Phase 2 Trial (Highdes).
Transplantation
; 105(8): 1808-1817, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093408
16.
Streptococcal Endo-ß-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo.
Front Immunol
; 9: 1623, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061892
17.
Alpha10 integrin expression is up-regulated on fibroblast growth factor-2-treated mesenchymal stem cells with improved chondrogenic differentiation potential.
Stem Cells Dev
; 16(6): 965-78, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18047418
18.
Expression of integrin alpha10 is induced in malignant melanoma.
Cell Oncol
; 29(5): 373-86, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17726260
19.
Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy.
Mol Cancer Ther
; 16(9): 1887-1897, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533435
20.
IgG-degrading enzyme of Streptococcus pyogenes (IdeS) prevents disease progression and facilitates improvement in a rabbit model of Guillain-Barré syndrome.
Exp Neurol
; 291: 134-140, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28214515