Detalhe da pesquisa
1.
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.
Nat Chem Biol
; 13(7): 771-778, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28530711
2.
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Nat Chem Biol
; 12(7): 504-10, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159579
3.
Targeting a cell state common to triple-negative breast cancers.
Mol Syst Biol
; 11(1): 789, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699542
4.
Ligand and structure-based classification models for prediction of P-glycoprotein inhibitors.
J Chem Inf Model
; 54(1): 218-29, 2014 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24050383
5.
Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues.
J Biol Chem
; 286(26): 23121-31, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21558271
6.
Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein.
PLoS Comput Biol
; 7(5): e1002036, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21589945
7.
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Nat Genet
; 51(6): 990-998, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133746
8.
Probing the stereoselectivity of P-glycoprotein-synthesis, biological activity and ligand docking studies of a set of enantiopure benzopyrano[3,4-b][1,4]oxazines.
Chem Commun (Camb)
; 47(9): 2586-8, 2011 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21173990
9.
Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design.
Mol Inform
; 29(4): 276-86, 2010 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27463054
10.
Using structural and mechanistic information to design novel inhibitors/substrates of P-glycoprotein.
Curr Top Med Chem
; 10(17): 1769-74, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20645918