Detalhe da pesquisa
1.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
; 629(8013): 919-926, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38589574
2.
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
J Biol Chem
; 297(5): 101335, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688654
3.
Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells.
J Biol Chem
; 295(15): 4796-4808, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071080
4.
The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction.
Biochem Soc Trans
; 49(1): 253-267, 2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544118
5.
Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE.
FASEB J
; 34(9): 12805-12819, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772419
6.
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
Am J Physiol Cell Physiol
; 316(1): C92-C103, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427721
7.
Mimicking transient activation of protein kinases in living cells.
Proc Natl Acad Sci U S A
; 113(52): 14976-14981, 2016 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956599
8.
Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer.
Science
; 384(6700): eadk0850, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843329
9.
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Science
; 384(6700): eadk0775, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843331
10.
VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer.
Genes Cancer
; 14: 30-49, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923647
11.
TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors.
Cancer Res
; 83(24): 4112-4129, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934103
12.
Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer.
Cancer Res
; 83(1): 141-157, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346366
13.
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.
Cell Rep
; 37(9): 110060, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852220
14.
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Cell Rep
; 35(13): 109291, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34192548
15.
Transcriptional coactivators are not required for herpes simplex virus type 1 immediate-early gene expression in vitro.
J Virol
; 83(8): 3436-49, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19176620
16.
Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis.
J Cell Biol
; 219(2)2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31865373
17.
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 26(6): 982, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483362
18.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Cancer Discov
; 10(1): 104-123, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31649109
19.
Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.
Cell Chem Biol
; 26(8): 1081-1094.e6, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31130521
20.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 25(4): 628-640, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833752