Detalhe da pesquisa
1.
PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.
Cell
; 144(5): 689-702, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376232
2.
Graphene Quantum Dots Alleviate Impaired Functions in Niemann-Pick Disease Type C in Vivo.
Nano Lett
; 21(5): 2339-2346, 2021 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472003
3.
Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson's Disease.
J Proteome Res
; 20(7): 3428-3443, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061533
4.
Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Proc Natl Acad Sci U S A
; 115(7): 1635-1640, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386392
5.
GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers.
Proc Natl Acad Sci U S A
; 115(4): 798-803, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311330
6.
Large and Externally Positioned Ligand-Coated Nanopatches Facilitate the Adhesion-Dependent Regenerative Polarization of Host Macrophages.
Nano Lett
; 20(10): 7272-7280, 2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32910662
7.
The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson's disease mouse model.
Hum Mol Genet
; 27(13): 2344-2356, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29897434
8.
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Brain
; 142(8): 2380-2401, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31237944
9.
Parkinson's disease gene therapy: Will focused ultrasound and nanovectors be the next frontier?
Mov Disord
; 34(9): 1279-1282, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30908781
10.
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Proc Natl Acad Sci U S A
; 108(34): 14103-8, 2011 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21825151
11.
DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 deficiency.
Genes Genomics
; 46(5): 519-529, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460098
12.
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.
Proc Natl Acad Sci U S A
; 107(38): 16691-6, 2010 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20823226
13.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Proc Natl Acad Sci U S A
; 107(1): 378-83, 2010 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19966284
14.
Advanced human iPSC-based preclinical model for Parkinson's disease with optogenetic alpha-synuclein aggregation.
Cell Stem Cell
; 30(7): 973-986.e11, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339636
15.
Linking Gba1 E326K mutation to microglia activation and mild age-dependent dopaminergic Neurodegeneration.
bioRxiv
; 2023 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745332
16.
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.
Proc Natl Acad Sci U S A
; 106(12): 4900-5, 2009 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19273858
17.
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Proc Natl Acad Sci U S A
; 106(8): 2897-902, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196961
18.
Levodopa-Induced Dyskinesia in Parkinson's Disease: Pathogenesis and Emerging Treatment Strategies.
Cells
; 11(23)2022 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36496996
19.
c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation.
Cells
; 11(24)2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36552734
20.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
Sci Adv
; 8(6): eabm6393, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35138901