Detalhe da pesquisa
1.
Autoinhibition of the GEF activity of cytoskeletal regulatory protein Trio is disrupted in neurodevelopmental disorder-related genetic variants.
J Biol Chem
; 298(9): 102361, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35963430
2.
Trio family proteins as regulators of cell migration and morphogenesis in development and disease - mechanisms and cellular contexts.
J Cell Sci
; 134(3)2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568469
3.
Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi.
Proc Natl Acad Sci U S A
; 117(48): 30380-30390, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184172
4.
Abl2:Cortactin Interactions Regulate Dendritic Spine Stability via Control of a Stable Filamentous Actin Pool.
J Neurosci
; 41(14): 3068-3081, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33622779
5.
Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation.
J Biol Chem
; 297(1): 100883, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34144039
6.
Functional interactions of ion channels with the actin cytoskeleton: does coupling to dynamic actin regulate NMDA receptors?
J Physiol
; 599(2): 431-441, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034761
7.
ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice.
Gastroenterology
; 159(1): 289-305.e16, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171747
8.
Correction: Trio family proteins as regulators of cell migration and morphogenesis in development and disease - mechanisms and cellular contexts.
J Cell Sci
; 136(3)2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36763488
9.
Cortactin stabilization of actin requires actin-binding repeats and linker, is disrupted by specific substitutions, and is independent of nucleotide state.
J Biol Chem
; 293(34): 13022-13032, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29929984
10.
Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity.
Hum Mol Genet
; 26(23): 4728-4740, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973398
11.
The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions.
J Allergy Clin Immunol
; 142(4): 1159-1172.e5, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29157947
12.
Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase.
Biochemistry
; 57(8): 1390-1398, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29341593
13.
Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disorders.
Annu Rev Neurosci
; 33: 349-78, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20367247
14.
The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.
J Cell Sci
; 129(16): 3130-43, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27358479
15.
Molecular mechanisms of dendrite stability.
Nat Rev Neurosci
; 14(8): 536-50, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23839597
16.
Corticosteroid-induced dendrite loss and behavioral deficiencies can be blocked by activation of Abl2/Arg kinase.
Mol Cell Neurosci
; 85: 226-234, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107098
17.
Disruption of Coordinated Presynaptic and Postsynaptic Maturation Underlies the Defects in Hippocampal Synapse Stability and Plasticity in Abl2/Arg-Deficient Mice.
J Neurosci
; 36(25): 6778-91, 2016 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27335408
18.
Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development.
J Neurosci Res
; 95(5): 1123-1143, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27735056
19.
Long-Term Live-Cell STED Nanoscopy of Primary and Cultured Cells with the Plasma Membrane HIDE Probe DiI-SiR.
Angew Chem Int Ed Engl
; 56(35): 10408-10412, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28679029
20.
Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.
J Biol Chem
; 290(7): 4038-46, 2015 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25540195