1.
J Org Chem
; 79(23): 11740-3, 2014 Dec 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25384091
RESUMO
Self-immolative aryl phthalate esters were conjugated with cleavable masking groups sensitive to light and hydrogen peroxide. The phthalate linker releases the fluorescent dye 7-hydroxycoumarin upon exposure to light or H2O2, respectively, leading to an increase in fluorescence. The light-sensitive aryl phthalate ester is demonstrated as a pro-fluorophore in cultured S2 cells.