Detalhe da pesquisa
1.
Leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Part II.
Bioorg Med Chem
; 27(6): 978-990, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737134
2.
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry.
Bioorg Med Chem
; 26(12): 3145-3157, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29859750
3.
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity.
J Med Chem
; 65(17): 11550-11573, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35939763
4.
Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability.
J Med Chem
; 64(24): 17992-18009, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34735766
5.
Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status.
J Med Chem
; 61(6): 2589-2603, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29499113
6.
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant.
J Med Chem
; 61(22): 9976-9999, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30365885
7.
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.
J Med Chem
; 61(14): 6379-6397, 2018 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29965752