Detalhe da pesquisa
1.
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders.
Med Res Rev
; 43(1): 55-211, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36111795
2.
Neurotoxicity evoked by organophosphates and available countermeasures.
Arch Toxicol
; 97(1): 39-72, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36335468
3.
A-agents, misleadingly known as "Novichoks": a narrative review.
Arch Toxicol
; 97(10): 2587-2607, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37612377
4.
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity.
Arch Toxicol
; 97(8): 2209-2217, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37221426
5.
Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK).
J Enzyme Inhib Med Chem
; 38(1): 2237209, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37489050
6.
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 24(11)2023 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298087
7.
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities.
J Enzyme Inhib Med Chem
; 37(1): 2605-2620, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36131624
8.
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
Molecules
; 27(3)2022 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164325
9.
Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
Bioorg Med Chem Lett
; 43: 128100, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33984470
10.
Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study.
Bioorg Med Chem Lett
; 51: 128374, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555506
11.
Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity.
Bioorg Chem
; 107: 104567, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33387730
12.
Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
Bioorg Chem
; 112: 104974, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34029971
13.
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimers drugs dealing with cholinergic, amyloid and mitochondrial systems.
Bioorg Chem
; 107: 104596, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33421953
14.
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
Arch Toxicol
; 95(3): 985-1001, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517499
15.
Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats.
Drug Chem Toxicol
; 44(2): 207-214, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31257938
16.
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies.
Int J Mol Sci
; 22(15)2021 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361074
17.
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.
Int J Mol Sci
; 22(8)2021 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33917200
18.
Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids.
Molecules
; 26(5)2021 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33652925
19.
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders.
Med Res Rev
; 40(5): 1593-1678, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32115745
20.
Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase.
J Nat Prod
; 83(5): 1359-1367, 2020 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32309949