Detalhe da pesquisa
1.
Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils.
J Biol Chem
; 299(4): 103072, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36849007
2.
Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats.
J Transl Med
; 21(1): 799, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37946197
3.
Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.
Respir Res
; 24(1): 133, 2023 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198686
4.
Alpha-1-Antitrypsin Protects Vascular Grafts of Brain-Dead Rats Against Ischemia/Reperfusion Injury.
J Surg Res
; 283: 953-964, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36915024
5.
Neutrophils play a major role in the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters.
Cell Mol Life Sci
; 79(12): 616, 2022 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460750
6.
Targeting Cathepsin C in PR3-ANCA Vasculitis.
J Am Soc Nephrol
; 33(5): 936-947, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35292437
7.
Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe.
Bioconjug Chem
; 32(8): 1782-1790, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34269060
8.
Gut Serpinome: Emerging Evidence in IBD.
Int J Mol Sci
; 22(11)2021 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34200095
9.
Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation.
Clin Proteomics
; 17: 23, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32549867
10.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
J Biol Chem
; 293(32): 12415-12428, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925593
11.
Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.
Pharmacol Rev
; 68(3): 603-30, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27329045
12.
Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis.
Int J Mol Sci
; 20(19)2019 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557781
13.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
J Biol Chem
; 291(16): 8486-99, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884336
14.
Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia.
Eur Respir J
; 57(4)2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33419887
15.
Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples.
Arch Biochem Biophys
; 612: 91-102, 2016 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746119
16.
New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.
J Biol Chem
; 289(46): 31777-31791, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288799
17.
Neutrophil serine proteases exert proteolytic activity on endothelial cells.
Kidney Int
; 88(4): 764-75, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061547
18.
Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway.
FASEB J
; 28(2): 740-51, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24225148
19.
A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.
J Biol Chem
; 288(37): 26635-48, 2013 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23902773
20.
Cathepsin C role in inflammatory gastroenterological, renal, rheumatic, and pulmonary disorders.
Biochimie
; 216: 175-180, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37758158