Detalhe da pesquisa
1.
Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.
Mol Cell
; 81(23): 4876-4890.e7, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739871
2.
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies.
Genome Biol
; 24(1): 284, 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38066546
3.
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.
bioRxiv
; 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116029
4.
Oncohistones: a roadmap to stalled development.
FEBS J
; 289(5): 1315-1328, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33969633
5.
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas.
Nat Genet
; 54(12): 1865-1880, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36471070
6.
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nat Cancer
; 3(5): 629-648, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35422502
7.
Polycomb repressive complex 2 in the driver's seat of childhood and young adult brain tumours.
Trends Cell Biol
; 31(10): 814-828, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34092471
8.
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation.
Cell Rep
; 33(7): 108390, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33207202
9.
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Nat Commun
; 10(1): 1262, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890717
10.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell
; 35(5): 782-797.e8, 2019 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085178
11.
Stalled developmental programs at the root of pediatric brain tumors.
Nat Genet
; 51(12): 1702-1713, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768071
12.
Optimizing laboratory test utilization in long-term acute care hospitals.
Proc (Bayl Univ Med Cent)
; 30(1): 26-29, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28127124
13.
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nat Cancer
; 3(7): 899, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739422
14.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell
; 36(3): 338-339, 2019 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31526762