Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 7 de 7
Filtrar
1.
Surg Today ; 41(10): 1395-400, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21922363

RESUMO

PURPOSE: Periodontitis has been associated with atherosclerotic cardiovascular lesions. There may be a link between periodontopathic bacterial infection and atherosclerosis. METHODS: In 53 patients with atherosclerosis, periodontal disease was classified according to the probing depth of the periodontal pocket. To compare the detection rate in different arterial lesion, specimens of diseased arteries (10 primary atherosclerotic lesions, 43 anastomotic lesions) and 21 control arteries without atherosclerotic findings macroscopically and microscopically in the arterial wall, obtained during the surgical procedures were examined for the presence of five species of putative periodontal bacteria using polymerase chain reaction (PCR) analysis. RESULTS: Fifty-one of the 53 patients (96%) had periodontitis, and 34 (64%) of those patients had severe periodontitis or were edentulous. In total, PCR analysis detected DNA specific for periodontal bacteria in 28 of the 53 specimens (52%) of atherosclerotic arterial wall. Only 5 of 21 (23%) were detected in control specimens. CONCLUSIONS: A high percentage of periodontopathic bacteria were detected in atherosclerotic arterial wall specimens from patients with atherosclerosis, especially with primary atherosclerotic lesions, and most cases had severe periodontitis.


Assuntos
Aterosclerose/microbiologia , Bactérias/isolamento & purificação , Periodontite/complicações , Idoso , Idoso de 80 Anos ou mais , Aterosclerose/complicações , Bactérias/genética , Bacteroidetes/genética , Bacteroidetes/isolamento & purificação , Estudos de Casos e Controles , DNA Bacteriano/química , DNA Bacteriano/isolamento & purificação , Humanos , Masculino , Pessoa de Meia-Idade , Pasteurellaceae/genética , Pasteurellaceae/isolamento & purificação , Bolsa Periodontal/complicações , Periodontite/microbiologia , Reação em Cadeia da Polimerase , Porphyromonas gingivalis/genética , Porphyromonas gingivalis/isolamento & purificação , Prevotella intermedia/genética , Prevotella intermedia/isolamento & purificação , Estudos Prospectivos , Treponema denticola/genética , Treponema denticola/isolamento & purificação
2.
Ann Vasc Dis ; 13(3): 322-325, 2020 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-33384739

RESUMO

Venous aneurysm (VA) is an uncommon vascular disease; however, VA, especially in the lower extremities, can lead to critical complications, such as pulmonary embolism (PE). We report a case with a VA located in the sural vein (SV), which did not lead to PE; however, it had the potential to cause PE. Therefore, we treated this VA by total excision. The popliteal vein (PV) is the most common VA location in the lower extremities, but SV is extremely rare. We should always be aware that, in addition to the PV, VAs may also occur in the SV.

3.
Ann Vasc Surg ; 22(3): 412-6, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18411025

RESUMO

Oral bacteria have been detected at atherosclerotic plaque, aneurysms, and thrombosed arteries in Buerger disease. We explored a possible relationship between the oral bacterium Porphyromonas gingivalis and arterial thrombosis at proximal and distal sites in rats. Eighteen rats underwent subcutaneous placement of an infusion pump connected to the jugular vein. The Pg infusion group received a continuous infusion of P. gingivalis for 2 weeks, and the controls received normal saline. At 2 and 4 weeks, specimens were obtained from the iliac, superficial, and below-knee arteries, which were studied pathologically and by polymerase chain reaction (PCR) analysis to detect P. gingivalis-specific DNA. The Pg infusion group had thrombosis in 33.3% at 2 weeks and in 55.6% at 4 weeks, but normal arterial wall structure was preserved without any features of infection. Positive PCR findings were recognized in 73.3% and 22.2% at 2 and 4 weeks, respectively. At 4 weeks, thrombosis was observed in a higher proportion, with the below-knee specimens having an especially high thrombus rate (83.3%). No control specimen had thrombosis or positive PCR results. Bacteremia due to the oral pathogen P. gingivalis may lead to thrombus formation in the peripheral arteries, especially in small-sized arteries.


Assuntos
Arteriopatias Oclusivas/microbiologia , Artérias/microbiologia , Infecções por Bacteroidaceae/complicações , Boca/microbiologia , Porphyromonas gingivalis/patogenicidade , Trombose/microbiologia , Animais , Arteriopatias Oclusivas/patologia , Artérias/patologia , Infecções por Bacteroidaceae/microbiologia , Infecções por Bacteroidaceae/patologia , DNA Viral/metabolismo , Modelos Animais de Doenças , Artéria Ilíaca/microbiologia , Bombas de Infusão Implantáveis , Infusões Intravenosas , Masculino , Reação em Cadeia da Polimerase , Porphyromonas gingivalis/genética , Ratos , Ratos Wistar , Trombose/patologia , Fatores de Tempo
4.
Ann Vasc Dis ; 9(4): 259-266, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-28018495

RESUMO

Objective: Endovenous laser ablation (EVLA) and radiofrequency ablation (RFA) are safe and effective treatments for varicose veins caused by saphenous reflux. Deep venous thrombosis (DVT) and endovenous heat-induced thrombosis (EHIT) are known complications of these procedures. The purpose of this article is to investigate the incidence of postoperative DVT and EHIT in patients undergoing EVLA and RFA. Methods: The patients were assessed by clinical examination and venous duplex ultrasonography before operation and at 24-72 hours, 1 month, and 1 year follow-up after operation. Endovenous ablation (EVA) had been treated for 1026 limbs (835 patients) using an RFA; 1174 limbs (954 patients) using a 1470-nm wavelength diode laser with radial two-ring fiber (1470R); and 6118 limbs (5513 patients) using a 980-nm wavelength diode laser with bare-tip fiber (980B). Results: DVT was detected in 3 legs (0.3%) of RFA, 5 legs (0.4%) of 1470R, and 27 legs (0.4%) of 980B. One patient in three symptomatic DVT treated with 980B developed asymptomatic pulmonary embolus. In all, 31 of the 35 DVTs were confined to the calf veins. The incidence of EHIT classes 2 and 3 was 2.7% following RFA procedure, 6.7% after 1470R, and 7.5% after 980B. Conclusion: The incidence of EHIT following EVA was low, especially the RFA procedure. EHIT resolves within 2-4 weeks in most patients. DVT rates after EVA were compared with those published for saphenous vein stripping. (This is a translation of J Jpn Coll Angiol 2015; 55: 153-161.).

5.
Ann Vasc Dis ; 7(3): 239-45, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25298824

RESUMO

OBJECTIVE: Major side effects after endovenous laser ablation (EVLA) are pain and bruising. The aim of this study was to compare outcome and side effects after EVLA for primary varicose veins with 1470 nm diode laser using bare-tip orradial fiber. METHODS: From October 2007 to December 2010, 385 patients (453 limbs) with primary varicose veins treated with 1470 nm laser were studied. Bare-tip fiber was used in 215 patients (242 limbs) (BF group) and radial fiber (ELVeS(TM)Radial, Biolitec AG, Germany) was used in 177 patients (211 limbs) (RF group). This study is a retrospective study and radial fiber was started for use from November 2008. Laser energy was administered at 6-12 W of power in the BF group and 10 W of power in the RF group with constant pullback of laser fiber under tumescent local anesthesia. The patients were assessed by clinical examination and venous duplex ultrasonography at 24-48 h, one week, one month, 4 months and one year follow-up postoperatively. RESULTS: Mean operating time, length of treated vein and linear endovenous laser energy of all cases were 42.6 min, 36.2 cm and 83.4 J/cm, respectively. Major complications such as deep vein thrombosis and skin burns were not noted. Bruising (1.9% vs. 19.4%) and pain (0.9% vs. 7.4%) were significantly lower in the RF group. Cumulative occlusion rates by Kaplan-Meier method were 100% at 32 months in the RF group and 99.5% at 4 years in the BF group. CONCLUSION: EVLA using 1470 nm laser with the radial fiber minimized adverse effects compared with bare-tip laser fiber. (English translation of Jpn J Vasc Surg 2013; 22: 615-621).

6.
Ann Vasc Dis ; 6(4): 702-5, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24386018

RESUMO

OBJECTIVE: The aim of this study was to assess the anatomical variations of the sapheno-femoral junction (SFJ) and the incidence of these variations. MATERIALS AND METHODS: Between April 2005 and March 2010, 2552 limbs of 1563 patients with complaints of varicose veins underwent ultrasonography. Ultrasonography was used to identify the anatomical variations of the SFJ, especially the relationship to the femoral artery. RESULTS: Variations were seen in six limbs (0.24%) at the SFJ. The most common anatomical variation was the great saphenous vein crossing posterior to the common femoral artery, which was present in three limbs. CONCLUSION: It is important to investigate the anomalies of the SFJ using preoperative duplex ultrasound, although the incidence of such anomalies is lower than that of the sapheno-popliteal junction. An anomaly of the SFJ always should be taken into consideration in order to minimize surgical complications of varicose veins. (English translation of Jpn J Phlebol 2012; 23: 25-29).

7.
J Vasc Surg ; 42(1): 107-15, 2005 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16012459

RESUMO

OBJECTIVE: Recent studies have suggested that infectious organisms play a role in vascular diseases. In this study, to explore a possible link between oral infection and Buerger disease, we investigated whether oral (periodontal) bacteria were present in occluded arteries removed from patients with characteristic Buerger disease. METHODS: Fourteen male patients with a smoking history who had developed characteristics of Buerger disease before the age of 50 years were included in this study. Occluded arteries, including superficial femoral (n = 4), popliteal (n = 2), anterior tibial (n = 4), and posterior tibial (n = 4) arteries, were removed and studied. A periodontist performed a periodontal examination on each patient and collected dental plaque and saliva samples from them at the same time. The polymerase chain reaction method was applied to detect whether seven species of periodontal bacteria--Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, Campylobacter rectus, Actinobacillus actinomycetemcomitans, Prevotella intermedia , and Prevotella nigrescens--were present in the occluded arteries and oral samples. In addition, arterial specimens from seven control patients were examined by polymerase chain reaction analysis. RESULTS: DNA of oral bacteria was detected in 13 of 14 arterial samples and all oral samples of patients with Buerger disease. Treponema denticola was found in 12 arterial and all oral samples. Campylobacter rectus, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis, and Prevotella nigrescens were found in 14% to 43% of the arterial samples and 71% to 100% of the oral samples. A pathologic examination revealed that arterial specimens showed the characteristics of an intermediate-chronic-stage or chronic-stage lesion of Buerger disease. All 14 patients with Buerger disease had moderate to severe periodontitis. None of the control arterial samples was positive for periodontal bacteria. CONCLUSIONS: This is the first study to identify oral microorganisms in the lesions of Buerger disease. Our findings suggest a possible etiologic link between Buerger disease and chronic infections such as oral bacterial infections.


Assuntos
Artérias/microbiologia , Placa Dentária/microbiologia , Saliva/microbiologia , Tromboangiite Obliterante/microbiologia , Adulto , Idoso , Infecções Bacterianas/epidemiologia , Doença Crônica , Comorbidade , DNA Bacteriano/isolamento & purificação , Humanos , Masculino , Pessoa de Meia-Idade , Tromboangiite Obliterante/epidemiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA