Detalhe da pesquisa
1.
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids.
J Cell Mol Med
; 27(3): 435-445, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36644817
2.
Unexpected neurotoxicity in chronic toxicity studies with a HBV viral expression inhibitor.
Regul Toxicol Pharmacol
; 141: 105407, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141985
3.
Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency.
Stem Cells
; 36(10): 1535-1551, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30004612
4.
Model-based assessment of erlotinib effect in vitro measured by real-time cell analysis.
J Pharmacokinet Pharmacodyn
; 42(3): 275-85, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25822652
5.
Retinal Microvasculature-on-a-Chip for Modeling VEGF-Induced Permeability.
Methods Mol Biol
; 2475: 239-257, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451763
6.
Optimization of the TeraTox Assay for Preclinical Teratogenicity Assessment.
Toxicol Sci
; 188(1): 17-33, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35485993
7.
Human immunocompetent choroid-on-chip: a novel tool for studying ocular effects of biological drugs.
Commun Biol
; 5(1): 52, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027657
8.
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina.
Stem Cells Transl Med
; 11(2): 159-177, 2022 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298655
9.
In vitro teratogenicity testing using a 3D, embryo-like gastruloid system.
Reprod Toxicol
; 105: 72-90, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34425190
10.
A Human Three-Dimensional In Vitro Model of Lens Epithelial Cells as a Model to Study Mechanisms of Drug-Induced Posterior Subcapsular Cataracts.
J Ocul Pharmacol Ther
; 36(1): 56-64, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31259661
11.
Organ-On-A-Chip Technologies for Advanced Blood-Retinal Barrier Models.
J Ocul Pharmacol Ther
; 36(1): 30-41, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31140899
12.
Focus on germ-layer markers: A human stem cell-based model for in vitro teratogenicity testing.
Reprod Toxicol
; 98: 286-298, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147516
13.
Human Retinal Microvasculature-on-a-Chip for Drug Discovery.
Adv Healthc Mater
; 9(21): e2001531, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32975047
14.
Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
ALTEX
; 37(1): 164, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31960940
15.
Organ-on-a-chip technologies that can transform ophthalmic drug discovery and disease modeling.
Expert Opin Drug Discov
; 14(1): 47-57, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30526132
16.
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
ALTEX
; 36(4): 682-699, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31658359
17.
Photoreceptor cell death mechanisms in inherited retinal degeneration.
Mol Neurobiol
; 38(3): 253-69, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18982459
18.
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA).
J Med Chem
; 61(15): 6501-6517, 2018 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044619
19.
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes.
Nat Commun
; 8(1): 262, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28811479
20.
Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine.
PLoS One
; 11(8): e0160807, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548442