Detalhe da pesquisa
1.
Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase.
J Enzyme Inhib Med Chem
; 38(1): 2231169, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37401012
2.
Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.
Molecules
; 28(16)2023 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37630415
3.
Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant.
Appl Microbiol Biotechnol
; 106(4): 1475-1492, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35092453
4.
The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors.
Int J Mol Sci
; 23(19)2022 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36232855
5.
Multilevel Approach for the Treatment of Giardiasis by Targeting Arginine Deiminase.
Int J Mol Sci
; 22(17)2021 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34502400
6.
Rabeprazole inhibits several functions of Entamoeba histolytica related with its virulence.
Parasitol Res
; 119(10): 3491-3502, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886229
7.
Proton pump inhibitors drastically modify triosephosphate isomerase from Giardia lamblia at functional and structural levels, providing molecular leads in the design of new antigiardiasic drugs.
Biochim Biophys Acta
; 1860(1 Pt A): 97-107, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26518348
8.
The oxidative fermentation of ethanol in Gluconacetobacter diazotrophicus is a two-step pathway catalyzed by a single enzyme: alcohol-aldehyde Dehydrogenase (ADHa).
Int J Mol Sci
; 16(1): 1293-311, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25574602
9.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
Biochim Biophys Acta
; 1834(12): 2702-11, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24056040
10.
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Antimicrob Agents Chemother
; 58(12): 7072-82, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25223993
11.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Int J Mol Sci
; 15(11): 21179-201, 2014 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25407525
12.
Safety of a dual potential prebiotic system from Mexican agave "Metlin® and Metlos®", incorporated to an infant formula for term newborn babies: a randomized controlled trial.
Rev Invest Clin
; 65(6): 483-90, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24687355
13.
ß(2 â 1)-ß(2 â 6) branched graminan-type fructans and ß(2 â 1) linear fructans impact mucus-related and endoplasmic reticulum stress-related genes in goblet cells and attenuate inflammatory responses in a fructan dependent fashion.
Food Funct
; 14(3): 1338-1348, 2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36656019
14.
TLR 2/1 interaction of pectin depends on its chemical structure and conformation.
Carbohydr Polym
; 303: 120444, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657837
15.
ß(2 â 1)-ß(2 â 6) and ß(2 â 1) fructans protect from impairment of intestinal tight junction's gene expression and attenuate human dendritic cell responses in a fructan-dependent fashion.
Carbohydr Polym
; 320: 121259, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37659831
16.
Is Your Kid Actin Out? A Series of Six Patients With Inherited Actin-Related Protein 2/3 Complex Subunit 1B Deficiency and Review of the Literature.
J Allergy Clin Immunol Pract
; 11(4): 1261-1280.e8, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36708766
17.
ß(2â1) chicory and ß(2â1)-ß(2â6) agave fructans protect the human intestinal barrier function in vitro in a stressor-dependent fashion.
Food Funct
; 13(12): 6737-6748, 2022 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665791
18.
Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial.
Gut Microbes
; 14(1): 2018899, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014600
19.
Naturally occurring deamidated triosephosphate isomerase is a promising target for cell-selective therapy in cancer.
Sci Rep
; 12(1): 4028, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35256749
20.
Not enough by half: NFAT5 haploinsufficiency in two patients with Epstein-Barr virus susceptibility.
Front Immunol
; 13: 959733, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36238298