Detalhe da pesquisa
1.
Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson's patient brain-derived α-synuclein.
J Neurosci Res
; 99(4): 1161-1176, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480104
2.
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification.
Alzheimers Dement
; 17(8): 1365-1382, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33559354
3.
Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer's Disease.
ACS Med Chem Lett
; 12(9): 1389-1395, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34531947
4.
A phase 1b randomized clinical trial of CT1812 to measure Aß oligomer displacement in Alzheimer's disease using an indwelling CSF catheter.
Transl Neurodegener
; 12(1): 24, 2023 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37173791