Detalhe da pesquisa
1.
Specificity for a CCR5 Inhibitor Is Conferred by a Single Amino Acid Residue: ROLE OF ILE198.
J Biol Chem
; 290(17): 11041-51, 2015 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25767113
2.
RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells.
Proc Natl Acad Sci U S A
; 110(33): 13522-7, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898169
3.
Discovery of a series of aryl-N-(3-(alkylamino)-5-(trifluoromethyl)phenyl)benzamides as TRPA1 antagonists.
Bioorg Med Chem Lett
; 24(14): 3204-6, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24880903
4.
Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists.
Bioorg Med Chem Lett
; 24(14): 3199-203, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24835202
5.
Discovery of P2X3 selective antagonists for the treatment of chronic pain.
Bioorg Med Chem Lett
; 22(7): 2565-71, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22370269
6.
Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.
J Am Chem Soc
; 133(41): 16477-85, 2011 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21942640
7.
Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.
Bioorg Med Chem Lett
; 21(8): 2450-5, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21398122
8.
A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery.
Methods Mol Biol
; 552: 153-69, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19513648
9.
Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.
Mol Pharmacol
; 74(6): 1485-95, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18768385
10.
Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.
Biochem Pharmacol
; 72(5): 588-96, 2006 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16815309
11.
The development of an europium-GTP assay to quantitate chemokine antagonist interactions for CXCR4 and CCR5.
Assay Drug Dev Technol
; 3(6): 637-48, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16438659
12.
Novel methodology to identify TRPV1 antagonists independent of capsaicin activation.
J Biomol Screen
; 18(5): 544-55, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264449
13.
The molecular pharmacology of AMD11070: an orally bioavailable CXCR4 HIV entry inhibitor.
Biochem Pharmacol
; 83(4): 472-9, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22146583
14.
HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay.
Virology
; 413(2): 231-43, 2011 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21388649
15.
Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4.
Biochem Pharmacol
; 78(8): 993-1000, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19540208
16.
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model.
Blood
; 106(12): 4002-8, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16105977
17.
Natriuretic peptide receptor A activation stabilizes a membrane-distal dimer interface.
J Biol Chem
; 278(13): 11159-66, 2003 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12547834
18.
Allotopic antagonism of the non-peptide atrial natriuretic peptide (ANP) antagonist HS-142-1 on natriuretic peptide receptor NPR-A.
Biochem J
; 362(Pt 1): 231-7, 2002 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11829760
19.
Investigation of the volatile organic substances that cause the characteristic odor of pentachlorophenol treated wood utility poles.
Environ Sci Technol
; 36(23): 5014-20, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12523414