RESUMO
In a mature ovarian cystic teratoma (MOCT) in a 67-year-old woman we found associated invasive squamous cell carcinoma and nodular amelanotic malignant melanoma. The finding of foci of typical and atypical melanocytic proliferation at the junctional level of the dermal component together with the absence of other possible sources supports an ovarian origin of the melanoma. A comparative analysis of the reported MOCT-associated malignant melanomas emphasizes the singularity of our case in the amelanotic character of the melanoma, its lymphotropism and the coexistence of invasive squamous cell carcinoma.
Assuntos
Carcinoma de Células Escamosas/patologia , Melanoma/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias Ovarianas/patologia , Teratoma/patologia , Idoso , Biomarcadores Tumorais/metabolismo , Carcinoma de Células Escamosas/metabolismo , Feminino , Humanos , Imuno-Histoquímica , Melanoma/metabolismo , Neoplasias Primárias Múltiplas/metabolismo , Neoplasias Ovarianas/metabolismo , Teratoma/metabolismoRESUMO
A case of a 72-year-old woman affected by angioimmunoblastic lymphadenopathy with dysproteinemia is described. She was admitted to the hospital for serious cutaneous lesions and dementia. The patient had been treated with corticosteroids for the previous two years. Cryptococcosis was diagnosed by cutaneous biopsy. Antimycotic therapy together with corticosteroid withdrawal cured the cutaneous lesions and improved her psychiatric symptoms.
Assuntos
Transtornos das Proteínas Sanguíneas/complicações , Criptococose/etiologia , Linfadenopatia Imunoblástica/complicações , Idoso , Biópsia , Transtornos das Proteínas Sanguíneas/patologia , Doença Crônica , Criptococose/tratamento farmacológico , Criptococose/patologia , Demência/etiologia , Demência/patologia , Feminino , Humanos , Linfadenopatia Imunoblástica/patologia , Imuno-Histoquímica , Pele/metabolismo , Pele/patologiaRESUMO
The main histological alteration that happens to the structure of the corpora cavernosa as years go by, is the progressive increase of collagen fibers compared to the decrease of both smooth muscle and elastic fibers. This phenomenon is held responsible of consequences on the hemodynamic events occurring during the erection.