Detalhe da pesquisa
1.
RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.
Int J Mol Sci
; 25(5)2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474284
2.
Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD).
Int J Mol Sci
; 24(6)2023 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982372
3.
Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance.
Magn Reson Chem
; 60(5): 504-514, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35075680
4.
Small-scale analysis of phytoecdysteroids in seeds by HPLC-DAD-MS for the identification and quantification of specific analogues, dereplication and chemotaxonomy.
Phytochem Anal
; 31(5): 643-661, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182633
5.
Size matters! Aurora A controls Drosophila larval development.
Dev Biol
; 440(2): 88-98, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29753017
6.
The effects of curcumin, mangiferin, resveratrol and other natural plant products on aminopeptidase B activity.
Biochem Biophys Res Commun
; 512(4): 832-837, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30928100
7.
The ecdysteroidome of Drosophila: influence of diet and development.
Development
; 142(21): 3758-68, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26395481
8.
The minor ecdysteroids from Ajuga turkestanica.
Phytochem Anal
; 26(5): 293-300, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25953625
9.
BIO101 stimulates myoblast differentiation and improves muscle function in adult and old mice.
J Cachexia Sarcopenia Muscle
; 15(1): 55-66, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064183
10.
Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial.
EClinicalMedicine
; 68: 102383, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545090
11.
The Distribution of Phytoecdysteroids among Terrestrial Vascular Plants: A Comparison of Two Databases and Discussion of the Implications for Plant/Insect Interactions and Plant Protection.
Plants (Basel)
; 12(4)2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840124
12.
A Phase 1 study for safety and pharmacokinetics of BIO101 (20-hydroxyecdysone) in healthy young and older adults.
J Cachexia Sarcopenia Muscle
; 14(3): 1259-1273, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37057316
13.
CYP18A1, a key enzyme of Drosophila steroid hormone inactivation, is essential for metamorphosis.
Dev Biol
; 349(1): 35-45, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20932968
14.
E- and Z-isomers of new phytoecdysteroid conjugates from French Polynesian Microsorum membranifolium (Polypodiaceae) fronds.
Molecules
; 17(10): 11598-606, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23023685
15.
High performance Reversed-Phase Thin-Layer Chromatography-Desorption electrospray ionisation - time of flight high resolution mass spectrometric detection and imaging (HPTLC/DESI/ToFMS) of phytoecdysteroids.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1200: 123265, 2022 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526348
16.
20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases.
Biomedicines
; 9(5)2021 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947076
17.
Developing new drugs that activate the protective arm of the renin-angiotensin system as a potential treatment for respiratory failure in COVID-19 patients.
Drug Discov Today
; 26(5): 1311-1318, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609783
18.
A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality.
Emerg Microbes Infect
; 10(1): 2256-2263, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783636
19.
20-Hydroxyecdysone activates the protective arm of the RAAS via the MAS receptor.
J Mol Endocrinol
; 68(2): 77-87, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825653
20.
The complex metabolism of poststerone in male rats.
J Steroid Biochem Mol Biol
; 212: 105897, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33862260