Detalhe da pesquisa
1.
Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Angew Chem Int Ed Engl
; 49(33): 5693-7, 2010 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20629058
2.
Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
J Med Chem
; 53(2): 633-40, 2010 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19957999
3.
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
J Med Chem
; 52(7): 1828-44, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19284751