Detalhe da pesquisa
1.
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics.
Int J Toxicol
; 42(6): 467-479, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37714565
2.
Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease.
Int J Toxicol
; 40(4): 322-336, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34255983
3.
Nonclinical Development of SRK-181: An Anti-Latent TGFß1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors.
Int J Toxicol
; 40(3): 226-241, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33739172
4.
Current strategies in the non-clinical safety assessment of biologics: New targets, new molecules, new challenges.
Regul Toxicol Pharmacol
; 98: 98-107, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30026135
5.
Nonclinical Development of ANX005: A Humanized Anti-C1q Antibody for Treatment of Autoimmune and Neurodegenerative Diseases.
Int J Toxicol
; 36(6): 449-462, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29202623
6.
An Introduction to the Regulatory and Nonclinical Aspects of the Nonclinical Development of Antibody Drug Conjugates.
Pharm Res
; 32(11): 3584-92, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108879
7.
The development of therapeutic monoclonal antibodies: overview of the nonclinical safety assessment.
Curr Pain Headache Rep
; 19(2): 2, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25681157
8.
Considerations regarding nonhuman primate use in safety assessment of biopharmaceuticals.
Int J Toxicol
; 30(5): 583-90, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22013138
9.
A 14-day repeat dose oral gavage range-finding study of a first-in-class CDI investigational antibiotic, in rats.
Sci Rep
; 9(1): 158, 2019 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655592
10.
Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design.
Curr Opin Toxicol
; 4: 1-15, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29658009
11.
Cosegregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetics.
Cancer Res
; 62(23): 6791-5, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12460886