Detalhe da pesquisa
1.
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.
Cell
; 168(1-2): 86-100.e15, 2017 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27916275
2.
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Nat Immunol
; 17(12): 1361-1372, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798618
3.
Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.
Mol Cell
; 68(4): 797-807.e7, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149600
4.
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure-Activity Relationship Models.
Chem Res Toxicol
; 36(7): 1028-1036, 2023 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327474
5.
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs.
Nat Chem Biol
; 16(4): 469-478, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152546
6.
Global survey of the immunomodulatory potential of common drugs.
Nat Chem Biol
; 13(6): 681-690, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28437395
7.
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.
Nat Chem Biol
; 13(7): 771-778, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28530711
8.
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Nat Chem Biol
; 12(7): 504-10, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159579
9.
Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity.
Nat Commun
; 15(1): 3470, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38658534
10.
Optimizing the Cell Painting assay for image-based profiling.
Nat Protoc
; 18(7): 1981-2013, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344608
11.
Quantitative proteomic analysis of A549 cells infected with human respiratory syncytial virus.
Mol Cell Proteomics
; 9(11): 2438-59, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20647383
12.
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.
Eur Urol
; 82(3): 261-270, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393162
13.
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
Mol Metab
; 54: 101329, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454092
14.
Mapping the perturbome network of cellular perturbations.
Nat Commun
; 10(1): 5140, 2019 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723137
15.
Mapping the Human Kinome in Response to DNA Damage.
Cell Rep
; 26(3): 555-563.e6, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30650350
16.
Pharmacologic inhibition of STAT5 in acute myeloid leukemia.
Leukemia
; 32(5): 1135-1146, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472718
17.
Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression.
Oncotarget
; 7(31): 50161-50179, 2016 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27367030