Detalhe da pesquisa
1.
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Nat Immunol
; 25(5): 764-777, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609546
2.
Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases.
Immunity
; 57(3): 429-445, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38479360
3.
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Nat Immunol
; 21(1): 54-64, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819256
4.
Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model.
Nat Immunol
; 20(4): 397-406, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742078
5.
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Immunity
; 55(3): 423-441.e9, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139355
6.
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Cell
; 157(5): 1175-88, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813849
7.
Sugar Fix Keeps RIPK3 at Bay.
Immunity
; 50(3): 539-541, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30893581
8.
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1ß release in X-linked inhibitor of apoptosis (XIAP) deficiency.
EMBO J
; 42(5): e110468, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36647737
9.
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
Nature
; 577(7788): 103-108, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827281
10.
A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation.
EMBO Rep
; 24(11): e56865, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37846472
11.
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease.
Semin Cell Dev Biol
; 109: 114-124, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32771377
12.
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Immunity
; 36(2): 215-27, 2012 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22365665
13.
Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1ß Secretion.
J Immunol
; 200(10): 3341-3346, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661823
14.
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Proc Natl Acad Sci U S A
; 114(6): E961-E969, 2017 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096356
15.
Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.
J Immunol
; 197(11): 4392-4402, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27807194
16.
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner.
Blood
; 123(16): 2562-72, 2014 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24497535
17.
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
EMBO Rep
; 15(9): 982-90, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990442
18.
Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria?
Biochim Biophys Acta
; 1840(4): 1433-40, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994495
19.
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation.
Cell Death Differ
; 31(5): 662-671, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514849
20.
Murine norovirus infection of macrophages induces intrinsic apoptosis as the major form of programmed cell death.
Virology
; 589: 109921, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939648