Detalhe da pesquisa
1.
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.
Mol Cell
; 39(3): 433-43, 2010 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20705244
2.
Immune modulatory mesenchymal stem cells derived from human embryonic stem cells through a trophoblast-like stage.
Stem Cells
; 34(2): 380-91, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26523849
3.
Inhibition of the mTORC2 and chaperone pathways to treat leukemia.
Blood
; 119(25): 6080-8, 2012 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566604
4.
Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.
Eur J Immunol
; 42(6): 1639-47, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22678916
5.
mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif.
J Biol Chem
; 286(16): 14190-8, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21321111
6.
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
EMBO J
; 27(14): 1932-43, 2008 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18566586
7.
DNA-PK Inhibitor Peposertib Amplifies Radiation-Induced Inflammatory Micronucleation and Enhances TGFß/PD-L1 Targeted Cancer Immunotherapy.
Mol Cancer Res
; 20(4): 568-582, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34980594
8.
Colocalized targeting of TGF-ß and PD-L1 by bintrafusp alfa elicits distinct antitumor responses.
J Immunother Cancer
; 10(7)2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858707
9.
Simultaneous targeting of TGF-ß/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion.
Cancer Cell
; 39(10): 1388-1403.e10, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506739
10.
E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells.
Mol Cell Biol
; 26(3): 810-21, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16428437
11.
Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc.
Cell Mol Immunol
; 16(9): 757-769, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705387
12.
Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Nat Cell Biol
; 21(5): 662-663, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30783264
13.
Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis.
Stem Cell Reports
; 16(2): 370-371, 2021 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33567293
14.
Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis.
Stem Cell Reports
; 3(1): 115-30, 2014 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25068126
15.
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Nat Cell Biol
; 15(11): 1340-50, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161930
16.
Perspectives on the role of mTORC2 in B lymphocyte development, immunity and tumorigenesis.
Protein Cell
; 2(7): 523-30, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822797
17.
E2A promotes the survival of precursor and mature B lymphocytes.
J Immunol
; 177(4): 2495-504, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16888011
18.
New insights into E-protein function in lymphocyte development.
Trends Immunol
; 26(6): 334-8, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15922950
19.
Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes.
J Biol Chem
; 279(43): 45028-35, 2004 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15310760