Detalhe da pesquisa
1.
Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype.
J Allergy Clin Immunol
; 152(5): 1303-1311.e1, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506976
2.
Successful treatment of JAK1-associated inflammatory disease.
J Allergy Clin Immunol
; 152(4): 972-983, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37343845
3.
Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition-Metal-Catalyzed Reactions.
Chemistry
; 29(44): e202301134, 2023 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37222167
4.
Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc Natl Acad Sci U S A
; 116(22): 10968-10977, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31076555
5.
Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B4.
Int J Mol Sci
; 23(23)2022 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36498943
6.
A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling.
Molecules
; 27(6)2022 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35335131
7.
A Promising Approach for Controlling the Second Coordination Sphere of Biomimetic Metal Complexes: Encapsulation in a Dynamic Hydrogen-Bonded Capsule.
Chemistry
; 27(1): 434-443, 2021 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33048410
8.
Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.
Org Biomol Chem
; 19(26): 5844-5866, 2021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115086
9.
Effect of uridine protecting groups on the diastereoselectivity of uridine-derived aldehyde 5'-alkynylation.
Beilstein J Org Chem
; 13: 1533-1541, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28845198
10.
Microwave-assisted preparation of 4-amino-3-cyano-5-methoxycarbonyl-N-arylpyrazoles as building blocks for the diversity-oriented synthesis of pyrazole-based polycyclic scaffolds.
Org Biomol Chem
; 13(2): 409-23, 2015 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25369050
11.
5'-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling.
Org Biomol Chem
; 13(26): 7193-222, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26008868
12.
Molecular modeling study of the induced-fit effect on kinase inhibition: the case of fibroblast growth factor receptor 3 (FGFR3).
J Comput Aided Mol Des
; 29(7): 619-41, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808135
13.
A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model.
Hum Mol Genet
; 21(4): 841-51, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072392
14.
Mechanism-based and computational modeling of hydrogen sulfide biogenesis inhibition: interfacial inhibition.
Sci Rep
; 13(1): 7287, 2023 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142727
15.
Persulfidation of DJ-1: Mechanism and Consequences.
Biomolecules
; 13(1)2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36671412
16.
New MraYAA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole.
Antibiotics (Basel)
; 11(9)2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139968
17.
Implication of folate deficiency in CYP2U1 loss of function.
J Exp Med
; 218(11)2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34546337
18.
Synthesis and biological evaluation of a triazole-based library of pyrido[2,3-d]pyrimidines as FGFR3 tyrosine kinase inhibitors.
Org Biomol Chem
; 8(9): 2164-73, 2010 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20401393
19.
Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor.
RSC Med Chem
; 11(5): 577-582, 2020 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479659
20.
Diagnosis traps for patients with acquired NLRP3 mutation.
Eur J Intern Med
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514289