Detalhe da pesquisa
1.
Compartmentalization and Selective Tagging for Disposal of Misfolded Glycoproteins.
Trends Biochem Sci
; 44(10): 827-836, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133362
2.
The Sigma-1 receptor is an ER-localized type II membrane protein.
J Biol Chem
; 297(5): 101299, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648767
3.
Pridopidine reduces mutant huntingtin-induced endoplasmic reticulum stress by modulation of the Sigma-1 receptor.
J Neurochem
; 158(2): 467-481, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33871049
4.
Letting go of O-glycans.
J Biol Chem
; 294(44): 15912-15913, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31676555
5.
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
Acta Neuropathol
; 140(5): 737-764, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32642868
6.
Glycan regulation of ER-associated degradation through compartmentalization.
Semin Cell Dev Biol
; 41: 99-109, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25460542
7.
Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling.
J Cell Sci
; 126(Pt 17): 3893-903, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23843619
8.
A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins.
J Biol Chem
; 288(4): 2167-78, 2013 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23233672
9.
Efficacy of therapy by MK-28 PERK activation in the Huntington's disease R6/2 mouse model.
Neurotherapeutics
; 21(2): e00335, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368172
10.
COP I and II dependent trafficking controls ER-associated degradation in mammalian cells.
iScience
; 26(3): 106232, 2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36876137
11.
Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
J Biol Chem
; 286(2): 1292-300, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21062743
12.
PERK Pathway and Neurodegenerative Disease: To Inhibit or to Activate?
Biomolecules
; 11(3)2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33652720
13.
A window of opportunity: timing protein degradation by trimming of sugars and ubiquitins.
Trends Biochem Sci
; 30(6): 297-303, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15950873
14.
Oxidoreductases in Glycoprotein Glycosylation, Folding, and ERAD.
Cells
; 9(9)2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32971745
15.
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.
Sci Rep
; 10(1): 6875, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327686
16.
Protein Misfolding and ER Stress in Huntington's Disease.
Front Mol Biosci
; 6: 20, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31001537
17.
Transient arrest in proteasomal degradation during inhibition of translation in the unfolded protein response.
Biochem J
; 404(3): 509-16, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17338678
18.
Mannosidase activity of EDEM1 and EDEM2 depends on an unfolded state of their glycoprotein substrates.
Commun Biol
; 1: 172, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374462
19.
ER stress induces alternative nonproteasomal degradation of ER proteins but not of cytosolic ones.
Cell Stress Chaperones
; 12(4): 373-83, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229456
20.
Separate roles and different routing of calnexin and ERp57 in endoplasmic reticulum quality control revealed by interactions with asialoglycoprotein receptor chains.
Mol Biol Cell
; 15(5): 2133-42, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-14978212