Detalhe da pesquisa
1.
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males.
Cereb Cortex
; 33(3): 844-864, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296883
2.
Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion.
Neurobiol Dis
; 182: 106141, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37121555
3.
Lipid-induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders.
EMBO J
; 38(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530526
4.
Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency.
Int J Mol Sci
; 24(11)2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298714
5.
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Mol Psychiatry
; 26(12): 7403-7416, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34584229
6.
NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation.
EMBO Rep
; 20(11): e48143, 2019 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535451
7.
Host sphingomyelin increases West Nile virus infection in vivo.
J Lipid Res
; 57(3): 422-32, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26764042
8.
WIP modulates dendritic spine actin cytoskeleton by transcriptional control of lipid metabolic enzymes.
Hum Mol Genet
; 23(16): 4383-95, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24698977
9.
Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS.
Neurobiol Dis
; 73: 319-26, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25251606
10.
Neurons regulate the esterification of bioactive lipid mediators in the brain of acid sphingomyelinase deficient mice.
Prog Neuropsychopharmacol Biol Psychiatry
; 129: 110896, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956788
11.
Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency.
Cell Death Dis
; 14(4): 248, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024473
12.
"MiR-7 controls cholesterol biosynthesis through posttranscriptional regulation of DHCR24 expression".
Biochim Biophys Acta Gene Regul Mech
; 1866(2): 194938, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37086967
13.
Models to study basic and applied aspects of lysosomal storage disorders.
Adv Drug Deliv Rev
; 190: 114532, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122863
14.
Efficacy and safety clinical trial with efavirenz in patients diagnosed with adult Niemann-pick type C with cognitive impairment.
Medicine (Baltimore)
; 101(48): e31471, 2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482560
15.
Brain cholesterol in normal and pathological aging.
Biochim Biophys Acta
; 1801(8): 934-44, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20359547
16.
Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice.
J Neurochem
; 116(5): 779-88, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21214563
17.
CERTL reduces C16 ceramide, amyloid-ß levels, and inflammation in a model of Alzheimer's disease.
Alzheimers Res Ther
; 13(1): 45, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597019
18.
Addressing neurodegeneration in lysosomal storage disorders: Advances in Niemann Pick diseases.
Neuropharmacology
; 171: 107851, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734384
19.
Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.
EMBO Mol Med
; 12(11): e11776, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33016621
20.
Neuronal membrane cholesterol loss enhances amyloid peptide generation.
J Cell Biol
; 167(5): 953-60, 2004 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15583033