Detalhe da pesquisa
1.
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease.
Proc Natl Acad Sci U S A
; 121(16): e2322924121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607933
2.
Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550.
Hum Mol Genet
; 32(1): 30-45, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35908190
3.
Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs.
Hum Mol Genet
; 30(3-4): 135-148, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33432339
4.
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Am J Hum Genet
; 107(1): 96-110, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589923
5.
Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Hum Mol Genet
; 29(18): 3044-3053, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32876667
6.
Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13.
Biochem Biophys Res Commun
; 521(3): 549-554, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31677786
7.
Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.
Hum Mol Genet
; 26(7): 1258-1267, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28165127
8.
Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA.
J Hum Genet
; 64(10): 995-1004, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296921
9.
IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway.
Life Sci Alliance
; 6(10)2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553253
10.
Sortilin is essential for proNGF-induced neuronal cell death.
Nature
; 427(6977): 843-8, 2004 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-14985763
11.
Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1.
J Neurosci
; 28(23): 5910-9, 2008 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18524895
12.
ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury.
Neuron
; 36(3): 375-86, 2002 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-12408842
13.
Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.
Mol Ther Nucleic Acids
; 11: 416-428, 2018 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29858077
14.
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.
J Neurosci
; 25(22): 5455-63, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15930396
15.
A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor.
J Neurosci
; 24(11): 2742-9, 2004 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15028767
16.
Human mutant huntingtin disrupts vocal learning in transgenic songbirds.
Nat Neurosci
; 18(11): 1617-22, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26436900
17.
Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.
Am J Pathol
; 166(2): 533-43, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15681836