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1.
Medicina (Kaunas) ; 59(11)2023 Nov 14.
Artigo em Inglês | MEDLINE | ID: mdl-38004045

RESUMO

Lumbar facet joints have been identified as a potential source of chronic low back pain (LBP) in 15% to 45% of patients, with the prevalence of such pain varying based on specific populations and settings examined. Lumbar facet joint interventions are useful in the diagnosis as well as the therapeutic management of chronic LBP. Radiofrequency ablation (RFA) of medial branch nerves is recognized as a safe and effective therapy for chronic facet joint pain in the lumbosacral spine, and its efficacy has already been established. The use of RFA is currently widespread in the management of spinal pain, but it is noteworthy that there have been works in the literature reporting complications, albeit at a very low frequency. We present a case of third-degree skin burns following radiofrequency ablation (RFA) for the management of facet joint syndrome. Postoperatively, the patient's skin encircling the needle displayed a pallor and exhibited deterioration in conjunction with the anatomical anomaly. The affected area required approximately 5 months to heal completely. During RFA, heat can induce burns not only at the point of contact with the RF electrode but also along the length of the needle. Vigilant attention is necessary to ensure patient safety and to address any potential complications that may arise during the procedure, including the possibility of minor technical errors.


Assuntos
Queimaduras , Ablação por Cateter , Dor Lombar , Bloqueio Nervoso , Ablação por Radiofrequência , Articulação Zigapofisária , Humanos , Articulação Zigapofisária/cirurgia , Dor Lombar/etiologia , Dor Lombar/cirurgia , Ablação por Radiofrequência/efeitos adversos , Bloqueio Nervoso/métodos , Artralgia , Ablação por Cateter/efeitos adversos , Ablação por Cateter/métodos
2.
BMC Ophthalmol ; 22(1): 383, 2022 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-36153503

RESUMO

BACKGROUND: To report about the therapy of benign eyelid tumors with a modified argon laser technique as an alternative to surgery. METHODS: Nineteen benign tumors of the eyelid were included in this study. After staining the surface of the tumor with a violet marker, low-energy argon laser photoablation was performed. A mean number of 312 spots (spot size ranging from 150 to 500 µm) with a power of 200 to 400 mW, and a duration between 0.1 and 0.2 s were applied. RESULTS: The eyelid tumors were located mainly in the lower eyelid (58%). Dermal nevi and papilloma were the most frequently treated lesions. Over a mean follow-up period of 10.5 months (range 6-18 months), all eyelid tumors were successfully treated by a single session of laser therapy. All patients were satisfied with the laser therapy and the cosmetic result. No postoperative complications were observed. No relapses occurred during follow-up. CONCLUSIONS: Our modified method of argon laser therapy utilizes the staining of the surface of the eyelid tumor to increase the amount of thermal laser energy absorbed by the target. This novel technique is simple and effective for treating benign eyelid tumors.


Assuntos
Neoplasias Palpebrais , Terapia a Laser , Argônio , Neoplasias Palpebrais/patologia , Neoplasias Palpebrais/radioterapia , Neoplasias Palpebrais/cirurgia , Pálpebras/patologia , Pálpebras/cirurgia , Seguimentos , Humanos , Terapia a Laser/métodos , Recidiva Local de Neoplasia
3.
Graefes Arch Clin Exp Ophthalmol ; 259(6): 1617-1623, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33415355

RESUMO

PURPOSE: To evaluate the passive duction force (PDF) in extraocular muscles (EOMs) in patients with intermittent exotropia (IXT) using a quantitative tension-measuring device. METHODS: This prospective, case-control study enrolled 25 patients with IXT and 26 age- and sex-matched controls. PDF was measured under general anesthesia as the eyeball was rotated medially or laterally away from the direction of the force being tested. The preferred eye for fixation was determined using a cover-uncover test. RESULTS: The PDF in the IXT and control groups were 60.9 g and 52.1 g, respectively, for the lateral rectus (LR) (p = 0.046) and 53.0 g and 48.8 g for the medial rectus (MR) (p = 0.293). When the eyes were examined separately in the IXT group, the PDF of LR was larger in the nonpreferred eye for fixation than in the control group (p = 0.039), whereas there was no difference in the preferred eye for fixation (p = 0.216). Additionally, the relative PDF of LR in the nonpreferred eye compared to the ipsilateral PDF of MR was positively associated with the duration of manifest deviation (p = 0.042) and the average angle of the near and far deviations (p = 0.023). CONCLUSIONS: The PDF in the LR in patients with IXT in the nonpreferred eye for fixation was larger than normal and could increase with the duration of manifest deviation and the angle of deviation. Evaluating the PDF in EOMs could provide information that is useful for managing strabismus and understanding its pathophysiology.


Assuntos
Exotropia , Estrabismo , Estudos de Casos e Controles , Exotropia/cirurgia , Humanos , Músculos Oculomotores/cirurgia , Estudos Prospectivos
4.
BMC Ophthalmol ; 21(1): 293, 2021 Aug 06.
Artigo em Inglês | MEDLINE | ID: mdl-34362336

RESUMO

BACKGROUND: This study aimed to determine the morphological changes in Asian lower eyelid epiblepharon patients after surgery. METHODS: The medical records of 59 patients who underwent lower eyelid epiblepharon repair were reviewed retrospectively. Eighty-nine patients who underwent strabismus surgery were set as the control group. The photographs for each group were analyzed based on the following factors: inferior half area (IHA) of the eye, eyelash angular direction (EAD), angle between the eyelashes and the cornea, marginal reflex distance 1 (MRD1) and marginal reflex distance 2 (MRD2). RESULTS: After surgery, the medial EAD changed from 92.45° ± 20.21° (mean ± SD) to 79.43° ± 23.31°, while the central and lateral EADs were unchanged. IHA increased from 36.33 ± 9.78 mm3 to 43.06 ± 10.57 mm3, and MRD1 increased from 1.92 ± 0.99 mm to 2.50 ± 0.93 mm, whereas MRD2 did not change. The mean angle between the eyelashes and the cornea increased from 39.64° to 72.19° immediately postoperatively, but had reduced to 58.75° 3 months later, followed by no further significant change at the 6-month and 9-month postoperative follow-ups. CONCLUSIONS: There is morphological changes of the eyelid after lower eyelid epiblepharon surgery, with increases in the IHA and MRD1. In addition, contact between the eyelashes and the cornea occurred mainly in the medial portion of the eyelid the position, which everted and stabilized over 3 months. Thus, follow-up observations are required for at least 3 months to properly evaluate the surgical outcome.


Assuntos
Pestanas , Doenças Palpebrais , Povo Asiático , Criança , Córnea , Doenças Palpebrais/cirurgia , Humanos , Músculos Oculomotores , Estudos Retrospectivos
5.
J Anat ; 237(5): 849-853, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32683709

RESUMO

This study aimed to elucidate the macroscopic and microscopic distributions of the dorsal nerve of penis (DNP) that provides the greatest sensitivity over the glans penis. The glandes of 23 penises of formalin-embalmed cadavers were investigated to confirm the macroscopic and microscopic distributions of the DNP within the glans penis by whole-mount Sihler's staining and histological sectioning. Superficial regions of the mid-glans were reconstructed in three dimensions to define the microstructure of terminal branches of the DNP that project towards the skin surface. A mean of 6.7 bundles of the DNP consisting of several nerve fibres converged linearly towards the distal end of the penis, rather than diverging laterally as they travelled. Lateral branches of the DNP extended linearly to the distal end with ramifications, while dorsomedial branches of the DNP gave off nerve fibres to the dorsum of the mid-glans and the corona. The intrastromal ramifications of the DNP were more developed in the distal half of the glans penis than the proximal glans containing the corpus cavernosum. These ramifications gave rise to radial nerve fibres that project towards the skin surface to form a plexiform network of terminal branches in the dermis. Linear projections of the main branches of the DNP throughout the glans and fine networks of terminal branches in the dermis were distinctly visualized in the human penis.


Assuntos
Pênis/inervação , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Pessoa de Meia-Idade
6.
Graefes Arch Clin Exp Ophthalmol ; 258(12): 2841-2848, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32803326

RESUMO

PURPOSE: Evaluating the passive duction force of the extraocular muscles is important for the diagnosis of and surgical planning for strabismus. This is especially relevant in patients with an observable limitation of duction movement. The purpose of this study was to validate passive duction forces in healthy subjects using a novel instrument. METHODS: An instrument for making continuous quantitative measurements of passive duction forces was designed. Tension was measured as the eyeball was rotated horizontally or vertically from the resting position under general anesthesia 10 mm (50°) away from the direction of force to be tested (opposite side). RESULTS: Seventy eyes of 35 subjects were enrolled in this study (age range of 4-80 years and mean age of 36.3 years). The passive duction force was measured at 49.0 ± 15.3 g (mean ± standard deviation) for medial rotation, 44.8 ± 13.2 g for lateral rotation, 50.5 ± 14.8 g for superior rotation, and 53.5 ± 13.8 g for inferior rotation. The passive duction forces were similar for all gaze positions, but it was larger for inferior rotation than for lateral rotation (P = 0.009). The passive duction force was significantly larger for vertical rotation (51.9 ± 14.4 g) than for horizontal rotation (46.9 ± 14.4 g) (P = 0.006). The passive duction force did not differ significantly with sex (P = 0.355), side (P = 0.087), or age (P = 0.872). CONCLUSIONS: These measurements of passive duction forces in a healthy population provide valuable information for diagnosing specific strabismic problems and could be useful for increasing the precision of strabismus surgery. Graphical abstract.


Assuntos
Oftalmologia , Estrabismo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Humanos , Pessoa de Meia-Idade , Músculos Oculomotores/cirurgia , Estrabismo/diagnóstico , Estrabismo/cirurgia , Adulto Jovem
7.
Clin Anat ; 33(8): 1159-1163, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31894604

RESUMO

PURPOSE: An infraorbital nerve (ION) block is widely used to accomplish regional anesthesia during surgical procedures involving the midface region. This study aimed to elucidate the exact location of the infraorbital foramen (IOF) in relation to clinically useful soft-tissue landmarks for achieving an effective ION block. METHODS: Forty-three hemifaces from 23 embalmed Korean cadavers were dissected. The lateral canthus, peak of Cupid's bow, medial limbus, and midline were used as reference points. The distances from the IOF to the midline and the lateral canthus were measured. RESULTS: The IOF was located approximately 25 mm below the lateral canthus and 27 mm lateral to the midline. In all cases, the IOF was situated within 9.0 mm of the crossing point of the oblique line connecting the lateral canthus to the peak of Cupid's bow and the vertical line through the medial limbus. CONCLUSION: Considering the spread of an anesthetic agent, injecting it into the crossing point of the oblique line through the lateral canthus to the peak of Cupid's bow and the vertical line through the medial limbus would successfully block the ION in most patients.


Assuntos
Pontos de Referência Anatômicos , Face/inervação , Ossos Faciais/anatomia & histologia , Idoso , Face/cirurgia , Feminino , Humanos , Masculino , Bloqueio Nervoso
8.
Surg Radiol Anat ; 42(10): 1255-1257, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32444934

RESUMO

The iliacus muscle is a large, flat, triangle-shaped muscle located in the iliac fossa. This muscle forms part of the iliopsoas muscle complex. Although anatomical variations of iliacus muscles are rare, some variations are clinically important due to the possible coexistence of an unusual course of the femoral nerve. The femoral nerve is the largest branch of the lumbar plexus and supplies the muscles and skin in the anterior aspect of the thigh. We encountered a case of a single aberrant slip of the iliacus muscle piercing the femoral nerve in the left iliac fossa of a male cadaver aged 97 years. The potential clinical importance of this variant iliacus muscle accompanied by a femoral nerve split would be femoral neuropathy and possible consequent alterations of sensation in the anterior and medial aspects of the thigh or motor deficit of the quadriceps muscle.


Assuntos
Variação Anatômica , Nervo Femoral/anormalidades , Neuropatia Femoral/etiologia , Músculo Esquelético/anormalidades , Síndromes de Compressão Nervosa/etiologia , Idoso de 80 Anos ou mais , Cadáver , Humanos , Ílio/inervação , Masculino
9.
J Anat ; 234(1): 83-88, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30450557

RESUMO

The corpus spongiosum reportedly occupies a larger proportion of the human glans penis than does the penile body, embedding the end of the corpus cavernosus (CC). However, anatomic descriptions about the fibrous structures of glans penis in the literature cause confusion during dissection and reconstructive surgery. Forty-five penises of formalin-embalmed cadavers were dissected sagittally along the course of the distal urethra and observed macroscopically. Dense connective tissues adjacent to the fossa navicularis and spongiosum parts of the glans were cropped, and underwent Masson's trichrome and Verhoeff-Van-Gieson staining. Most (55.5%) of the specimens had distinct fibrous bands toward the distal tips of the glans penis, which elongated from the tunica albuginea of the CC. They comprised longitudinal collagen bundles continuous to the outer longitudinal layer of the tunica albuginea covering the CC and were intermingled with sparse elastic fibres. This architecture either did not reach the distal end of the glans penis (35.5% of cases), or was obscure or dispersed in all directions (9.0% of cases). The structural dimorphism and the variations in the ratio of dense connective tissue components of the fibrous skeleton are considered to contribute to the varying degrees of flexibility, distensibility and rigidity of the human glans penis.


Assuntos
Ligamentos/anatomia & histologia , Ligamentos/citologia , Pênis/anatomia & histologia , Pênis/citologia , Idoso , Idoso de 80 Anos ou mais , Cadáver , Humanos , Ligamentos/patologia , Masculino , Pessoa de Meia-Idade , Pênis/patologia
10.
Clin Anat ; 32(5): 630-634, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30807676

RESUMO

Successful oculofacial procedures require the availability of a reliable surgical and anatomic landmark. This study aimed to determine the usefulness of the lateral canthus as a surface landmark. Seventy-seven from 42 Korean cadavers were dissected. The horizontal distance from the lateral canthus to the lateral orbital margin and the vertical distances from the zygomaticofrontal suture and the inferior orbital margin to the lateral canthus were measured. The mean horizontal distance from the lateral canthus to the lateral orbital margin was 7.8 mm. Although the horizontal position of the lateral canthus appears to alter with age, the variation was only 2-3 mm. The mean vertical distances from the zygomaticofrontal suture and inferior orbital margin to the lateral canthus were 8.1 and 17.2 mm. The vertical position of the lateral canthus did not vary with age, being located inferiorly within a fingernail width from the zygomaticofrontal suture. The lateral canthus, which is easily accessible and supported by muscular and fibrous lateral orbital attachments, exhibits small anatomic variations. Thus, the lateral canthus could act as a reliable surface landmark for identifying the location of underlying structures and describing a lesion on the face. Clin. Anat. 32:630-634, 2019. © 2019 Wiley Periodicals, Inc.


Assuntos
Pontos de Referência Anatômicos , Aparelho Lacrimal/anatomia & histologia , Órbita/anatomia & histologia , Cadáver , Feminino , Humanos , Masculino
11.
Graefes Arch Clin Exp Ophthalmol ; 256(10): 1993-2000, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29858678

RESUMO

PURPOSE: To determine the effect of granuloma formation in the ostium and intralesional steroid injections (ISIs) on the surgical outcome after endoscopic dacryocystorhinostomy (DCR) in patients with primary acquired nasolacrimal duct obstruction (PANDO). METHODS: One hundred and eighty-three cases involving 142 patients were enrolled. The ostium granulomas were classified according to their location relative to the internal common opening (superior, anterior, and posterior positions) and to the vicinity of the ostium (inner, edge, and extra types). If an ostium granuloma was observed during the follow-up and its size increased, ISIs were performed using 0.3 ml of 40 mg/ml triamcinolone acetonide. The surgical outcomes were compared between cases with and without ostium granulomas and also between each granuloma position and type. RESULTS: Ostium granulomas occurred in 71 (38.8%) of the 183 cases, and an ISI was applied in 65 cases with a mean of 2.1 injections. All of the granulomas regressed successfully after ISIs, with the success rate not differing between the cases with (85.9%) and without (83.9%) granuloma. There was no association between granuloma location and surgical outcome. However, the functional outcome was worse (60%) for inner granulomas (which are located within the ostial base) than for extra (87.8%) and edge (98%) granulomas. CONCLUSIONS: ISIs can be easily applied by a surgeon to help regress an ostium granuloma and improve the ostial patency after DCR. Inner ostium granulomas are associated with a worse functional outcome, and the initiation of an early corrective intervention such as an ISI should be considered.


Assuntos
Dacriocistorinostomia/métodos , Endoscopia/métodos , Glucocorticoides/administração & dosagem , Granuloma/complicações , Obstrução dos Ductos Lacrimais/terapia , Ducto Nasolacrimal/cirurgia , Adulto , Idoso , Feminino , Seguimentos , Granuloma/diagnóstico , Granuloma/terapia , Humanos , Injeções Intralesionais , Obstrução dos Ductos Lacrimais/diagnóstico , Obstrução dos Ductos Lacrimais/etiologia , Masculino , Pessoa de Meia-Idade , Ducto Nasolacrimal/efeitos dos fármacos , Estudos Retrospectivos , Resultado do Tratamento
12.
J Craniofac Surg ; 29(8): 2353-2357, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30334915

RESUMO

PURPOSE: This study evaluated midfacial asymmetry using an alternative method that involved comparing bilateral patterns of the zygomaticomaxillary prominence in a young adult population. MATERIALS AND METHODS: Three-dimensional reconstructed images based on computed tomography scans of 100 Koreans (mean age, 24.7 years) were evaluated with reference to lines spaced at 30° intervals and radiating from the center of an interporion line in a superior view. The surface inclination of the zygomaticomaxillary region was quantified on the same reference lines using a 3-dimensional ruler. RESULTS: The 30°-interval line (at the level of the zygomaticotemporal suture) was longer on the left side than the right side in both males and females, whereas the left 60°-interval line (at the level of the zygomaticofrontal suture) was longer in females. Comparing the surface protrusion revealed that the zygomaticomaxillary region was more prognathic and inflated on the left side. CONCLUSION: Functional deviations are considered to be causes of asymmetric craniofacial growth. Postnatal growth allometry across the circummaxillary sutures as elucidated by this study could be useful information in craniofacial surgery.


Assuntos
Assimetria Facial/diagnóstico por imagem , Assimetria Facial/patologia , Adulto , Bochecha , Feminino , Humanos , Imageamento Tridimensional , Masculino , República da Coreia , Tomografia Computadorizada por Raios X , Adulto Jovem
13.
Clin Anat ; 31(4): 608-613, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29226469

RESUMO

To investigate the topographical relationship between the frontal branch of the superficial temporal artery (FSTA) and the temporal branch of the facial nerve (TFN) with the aim of preventing nerve injury during FSTA biopsy. Fifty-seven hemifaces of 33 cadavers were dissected. Vertical lines drawn to the lateral orbital margin (LOM) and the superior root of the helix were used as the anterior and posterior reference positions, respectively. Horizontal lines drawn through the supraorbital margin and lateral canthus were used as the superior and inferior reference points, respectively. The depth and course relationships of the FSTA and TFN were examined. Midpoints between the FSTA and TFN are situated approximately 6.0 and 4.5 cm posterior to the lateral orbital margin at the levels of the lateral canthus and supraorbital margin, respectively. The TFN is generally situated 1-2 cm anteriorly and inferiorly to the FSTA in the temporal region. However, in two cases (3.6%), the TFN ran just underneath the FSTA with only a very small safe distance, making it highly vulnerable to iatrogenic injury. In conclusion, when performing an FSTA biopsy, the surgeon should not dissect below the superficial temporal fascia because there is an overlap between the course of the FSTA and the TFN in a minority of cases. Also, surgical incisions should be made outside the area delineated by an oblique line passing through the points 6.0 and 4.5 cm posterior to the lateral orbital margin at the levels of the lateral canthus and the supraorbital margin, respectively. Clin. Anat. 31:608-613, 2018. © 2017 Wiley Periodicals, Inc.


Assuntos
Nervo Facial/anatomia & histologia , Artérias Temporais/anatomia & histologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Artérias Temporais/cirurgia
14.
J Anat ; 231(5): 683-689, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28695607

RESUMO

Posterior projections of the ophthalmic division of the trigeminal nerve (the ophthalmic nerve) are distributed in the tentorium cerebelli as recurrent meningeal branches. We investigated the morphological tentorial distribution of the ophthalmic nerve. Fifty-two sides of the tentorium cerebelli and adjacent dura mater obtained from 29 human specimens were stained using Sihler's method to examine the nerve fibres in the dural sheets. The innervation patterns of the tentorium cerebelli were classified into the following four types according to their distributions: Type 1, where nerve fibres projected to both the straight and transverse sinuses; Type 2, where nerve fibres projected only to the transverse sinus and lateral convexity; Type 3, where nerve fibres projected medially only to the straight sinus and the posterior part of the falx cerebri; and Type 4, where the nerve fibres terminated within the tentorium cerebelli. Images of the tentorium cerebelli were superimposed to identify areas of dense innervation. The incidence rates of Types 1-4 were 71.2% (n = 37), 21.2% (n = 11), 3.8% (n = 2) and 3.8% (n = 2), respectively. More branches of nerve fibres traversed towards the transverse sinus posterolaterally than towards the straight sinus medially. The space between the anterior half of the straight sinus and the medial tentorial notch can be considered a safe surgical area where innervation is scarce. The posterior part of the falx cerebri was innervated by the ophthalmic nerve that traversed to the straight sinus. The parietal branches of the middle meningeal artery in the lateral convexity that were projected orthogonally by the ophthalmic nerve traversed the transverse sinus, implicating their vulnerability and possible sensitivity under physiological or neurosurgical conditions. This study has revealed the macroscopic tentorial innervation of the dura mater in humans, which could be useful information for both neurosurgeons and neurologists.


Assuntos
Dura-Máter/anatomia & histologia , Medula Espinal/anatomia & histologia , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
15.
Muscle Nerve ; 55(5): 646-650, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-27543938

RESUMO

INTRODUCTION: Compression of the lateral femoral cutaneous nerve (LFCN), known as meralgia paresthetica (MP), is common. We investigated the topographic anatomy of the LFCN focusing on the inguinal ligament and adjacent structures. METHODS: Distances from various bony and soft-tissue landmarks to the LFCN were investigated in 33 formalin-embalmed cadavers. RESULTS: The mean distance from the anterior superior iliac spine (ASIS) to the LFCN was 8.8 mm. In approximately 90% of cases, the LFCN lay <2 cm from the medial tip of the ASIS, whereas, in 76% of cases, it was <1 cm away. The mean angle between the inguinal ligament and LFCN was 83.3°. CONCLUSIONS: We determined the variability of the location of the LFCN at the boundary between the pelvic and femoral portions. The reported results will be helpful for diagnosis and treatment of MP. Muscle Nerve 55: 646-650, 2017.


Assuntos
Nervo Femoral/anatomia & histologia , Síndromes de Compressão Nervosa/patologia , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Neuropatia Femoral , Humanos , Masculino , Pessoa de Meia-Idade , Coxa da Perna/inervação
16.
Dermatol Surg ; 43(12): 1458-1465, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28614090

RESUMO

BACKGROUND: The supratrochlear nerve (STN) is relatively superficial and therefore vulnerable to iatrogenic injury. OBJECTIVE: To elucidate the course of STN with reference to the lacrimal caruncle, with the aim of preventing nerve injury during surgery in the forehead region. MATERIALS AND METHODS: Thirty-four hemifaces from 18 Korean cadavers were dissected. The vertical line through the apex of lacrimal caruncle and the horizontal line through the supraorbital margin were used as horizontal and vertical reference lines, respectively. The course of STN in the frontal view and the point at which it pierced the overlaying musculature were examined. RESULTS: After exiting the corrugator muscle cushion, the STN enters the subcutaneous plane by piercing the frontalis muscle. These piercing points occurred at mean horizontal and vertical distances relative to the medial branch of the STN of 9.2 and 9.6 mm, respectively; the corresponding distances for the lateral branch of the STN were 1.1 and 15.3 mm, respectively. CONCLUSION: When performing surgery in the medial forehead region, the surgeon must ensure that the dissection plane of forehead tissue is more superficial: superiorly within 1.5 cm from the supraorbital margin and medially within 1.0 cm from the vertical line through the apex of lacrimal caruncle.


Assuntos
Procedimentos Cirúrgicos Dermatológicos/efeitos adversos , Testa/inervação , Traumatismos do Nervo Trigêmeo/prevenção & controle , Nervo Trigêmeo/anatomia & histologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Povo Asiático , Cadáver , Dissecação , Feminino , Testa/anatomia & histologia , Testa/cirurgia , Humanos , Aparelho Lacrimal/anatomia & histologia , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/efeitos adversos , Nervo Trigêmeo/cirurgia , Traumatismos do Nervo Trigêmeo/etiologia
17.
Dermatol Surg ; 42(8): 992-8, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27355574

RESUMO

BACKGROUND: Blocking the supraorbital nerve (SON) and supratrochlear nerve (STN) by injecting anesthetic distal to the surgical site has the advantage in upper eyelid surgery that avoids obscuring the surgical landmarks and compromising the levator function. OBJECTIVE: To identify the emerging points of the SON and STN in the supraorbital margin with reference to the lacrimal caruncle. METHODS: Forty-nine orbits from 27 embalmed Korean cadavers were dissected. The lacrimal caruncle and facial midline were used as landmarks. The emerging points of the SON and STN in the supraorbital margin were determined. RESULTS: The emerging points of the SON and STN were, respectively, located at 3.0 mm lateral and 3.3 mm medial to the vertical line through the apex of the lacrimal caruncle along the supraorbital margin. The horizontal distances from the facial midline to the emerging points of the SON and STN were 22.8 and 15.2 mm, respectively. CONCLUSION: The optimum sites for achieving SON and STN block are, respectively, located approximately 3 mm lateral and 3 mm medial to the vertical line through the apex of lacrimal caruncle along the supraorbital margin. This knowledge will help the surgeon achieve an easy and accurate approach for regional nerve block.


Assuntos
Pálpebras/inervação , Pálpebras/cirurgia , Aparelho Lacrimal/anatomia & histologia , Bloqueio Nervoso , Adulto , Idoso , Idoso de 80 Anos ou mais , Pontos de Referência Anatômicos , Cadáver , Dissecação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
18.
J Craniofac Surg ; 27(7): 1854-1857, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27513782

RESUMO

PURPOSE: The aim of the study was to elucidate the positional relationship of the ethmoidal foramens (EFs) with reference to the nasion to facilitate prediction of the exact location of EFs, the optic canal (OC), and the frontoethmoidal suture (FS), and thereby avoid complications during complex surgery involving the medial wall of the orbit. MATERIALS AND METHODS: One hundred two intact orbits of 57 embalmed cadavers were dissected in this observational anatomic study. Nasion' (N') was defined as the intersection point of the medial orbit margin with the horizontal line through the nasion, and this was used as a reference point. N'-OC was defined as the straight line joining N' and OC. The locations of the anterior ethmoidal foramen (AEF), posterior ethmoidal foramen (PEF), and OC were determined with reference to N'. The vertical distances from N'-OC to EFs and to FS were also determined. RESULTS: The N'-AEF, AEF-PEF, and PEF-OC distances were 18.4, 15.3, and 8.3 mm, respectively. Vertically, AEF and PEF were situated at 0.2 mm below and 0.4 mm above N'-OC, respectively. At the same reference points, N'-OC was situated at 0.4 and 0.6 mm above FS, respectively. CONCLUSIONS: N', AEF, PEF, and OC were considered to be situated on the same straight line, and N'-OC could be regarded as coinciding with FS. This means that N' is an easily identifiable and reliable landmark for identifying EFs, OC, and FS. Our navigational parameters with reference to N' will help surgeons to enhance the safety of orbital surgery.


Assuntos
Suturas Cranianas/anatomia & histologia , Osso Etmoide/anatomia & histologia , Procedimentos Cirúrgicos Oftalmológicos , Órbita/anatomia & histologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Osso Etmoide/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Órbita/cirurgia
19.
Genes Chromosomes Cancer ; 54(1): 20-7, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25145975

RESUMO

We performed single nucleotide polymorphism (SNP) array analysis of 35 newly diagnosed symptomatic multiple myeloma (MM) patients who received bortezomib-melphalan-prednisone (VMP) to identify collaborating genetic events that could predict the outcome of treatment. A total of 340 copy number variations (CNVs) were identified, with the most frequently identified CNVs being gains on 1q, 19p, 9q, 3q, 9p, 15q, 19q, 5q, 11q, 5p, and 7q and losses on 1p, X, 13q, 14q, and 6q. The number and proportion of detected abnormalities by SNP array were associated with presence of cytogenetic abnormalities and complex karyotype. Moreover, increasing genomic complexity as ascertained by SNP arrays correlated with outcome of the VMP treatment. The frequency of CNVs was significantly different according to achievement of very good partial response (VGPR) to VMP treatment (

Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Variações do Número de Cópias de DNA , Mieloma Múltiplo/tratamento farmacológico , Adulto , Idoso , Idoso de 80 Anos ou mais , Ácidos Borônicos/administração & dosagem , Bortezomib , Cromossomos Humanos/genética , Feminino , Humanos , Masculino , Melfalan/administração & dosagem , Pessoa de Meia-Idade , Mieloma Múltiplo/genética , Polimorfismo de Nucleotídeo Único , Prednisona/administração & dosagem , Pirazinas/administração & dosagem
20.
Cornea ; 2024 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-38951743

RESUMO

PURPOSE: To evaluate the effectiveness of conjunctival cyst ablation using pattern scan laser photoablation. METHODS: Ninety-four cases of symptomatic conjunctival cysts were included. After staining the surface of a conjunctival cyst with a dark-purple marker pen, an incision was made into the conjunctival cyst using a 26-gauge needle. Low-energy photoablation using 3 × 3 grids of spots was then applied around the incision site for a mean of 50 times. The laser spots were 400 µm in size, the power delivered ranged from 400 to 450 mW, and the duration of each laser pulse was 80 ms. RESULTS: During a mean follow-up period of 6.5 months (range 6-16 months), 84 cases of conjunctival cysts (89.4%) were successfully corrected by conducting either 1 or 2 laser sessions. The cyst was completely resolved after a single laser session in 74 cases (78.7%). There were 20 cases of recurrence, which involved fixed, thick, and large cysts. The conjunctival cyst recurred again after the second laser session in 2 of the 12 eyes in which the procedure was repeated. The remaining 8 cases were observed without additional treatment. No postoperative complications such as conjunctival scarring or persistent ocular irritation were observed. CONCLUSIONS: Pattern scan laser photoablation of a conjunctival cyst with the adjunctive use of cyst surface staining to increase the amount of thermal laser energy absorption is a simple and effective method for treating conjunctival cysts in an outpatient clinic.

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