Detalhe da pesquisa
1.
Vitamin B12 inhibits peptidylarginine deiminases and ameliorates rheumatoid arthritis in CAIA mice.
Biochem Biophys Res Commun
; 704: 149668, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401303
2.
Discovery of M Protease Inhibitors Encoded by SARS-CoV-2.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669265
3.
Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1α.
Pharmacol Res
; 152: 104581, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794869
4.
Polyketide Synthase Gene Expression in Relation to Chloromonilicin and Melanin Production in Monilinia fructicola.
Phytopathology
; 110(8): 1465-1475, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32286920
5.
The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling.
Toxicol Appl Pharmacol
; 356: 90-97, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30053394
6.
Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus.
Toxicol Appl Pharmacol
; 332: 129-137, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438630
7.
Biological evaluation of secondary metabolites from the root of Machilus obovatifolia.
Chem Biodivers
; 12(7): 1057-67, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26172326
8.
A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease.
Antimicrob Agents Chemother
; 58(1): 110-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145533
9.
c-Jun-mediated anticancer mechanisms of tylophorine.
Carcinogenesis
; 34(6): 1304-14, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385061
10.
Correction: Lee et al. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics 2022, 14, 1511.
Pharmaceutics
; 15(2)2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840037
11.
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin.
Biochem Pharmacol
; 215: 115688, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481137
12.
Tyrphostin AG1024 Suppresses Coronaviral Replication by Downregulating JAK1 via an IR/IGF-1R Independent Proteolysis Mediated by Ndfip1/2_NEDD4-like E3 Ligase Itch.
Pharmaceuticals (Basel)
; 15(2)2022 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35215353
13.
The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b.
Pharmaceutics
; 14(7)2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890406
14.
Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay.
Antimicrob Agents Chemother
; 55(1): 229-38, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937790
15.
Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of Ardisia cornudentata.
Planta Med
; 77(1): 60-5, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20607650
16.
Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the Formosan Tylophora ovata.
Planta Med
; 77(17): 1932-8, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21728149
17.
Remdesivir and Cyclosporine Synergistically Inhibit the Human Coronaviruses OC43 and SARS-CoV-2.
Front Pharmacol
; 12: 706901, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34483914
18.
Cytotoxic flavonoids from the leaves of Cryptocarya chinensis.
J Nat Prod
; 73(9): 1470-5, 2010 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20704331
19.
Cytotoxic sesquiterpenes from Magnolia kachirachirai.
Chem Biodivers
; 7(11): 2737-47, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21072773
20.
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysis.
Biochem Pharmacol
; 180: 114122, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32592721