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1.
Environ Health ; 17(1): 27, 2018 03 27.
Artigo em Inglês | MEDLINE | ID: mdl-29587831

RESUMO

BACKGROUND: Studies of potential adverse effects of traffic related air pollution (TRAP) on allergic disease have had mixed findings. Nutritional studies to examine whether fish oil supplementation may protect against development of allergic disease through their anti-inflammatory actions have also had mixed findings. Extremely few studies to date have considered whether air pollution and dietary factors such as fish oil intake may interact, which was the rationale for this study. METHODS: We conducted a secondary analysis of the Childhood Asthma Prevention Study (CAPS) birth cohort, where children were randomised to fish oil supplementation or placebo from early life to age 5 years. We examined interactions between supplementation and TRAP (using weighted road density at place of residence as our measure of traffic related air pollution exposure) with allergic disease and lung function outcomes at age 5 and 8 years. RESULTS: Outcome information was available on approximately 400 children (~ 70% of the original birth cohort). Statistically significant interactions between fish oil supplementation and TRAP were seen for house dust mite (HDM), inhalant and all-allergen skin prick tests (SPTs) and for HDM-specific interleukin-5 response at age 5. Adjusting for relevant confounders, relative risks (RRs) for positive HDM SPT were RR 1.74 (95% CI 1.22-2.48) per 100 m local road or 33.3 m of motorway within 50 m of the home for those randomised to the control group and 1.03 (0.76-1.41) for those randomised to receive the fish oil supplement. The risk differential was highest in an analysis restricted to those who did not change address between ages 5 and 8 years. In this sub-group, supplementation also protected against the effect of traffic exposure on pre-bronchodilator FEV1/FVC ratio. CONCLUSIONS: Results suggest that fish oil supplementation may protect against pro-allergic sensitisation effects of TRAP exposure. Strengths of this analysis are that supplementation was randomised and independent of TRAP exposure, however, findings need to be confirmed in a larger experimental study with the interaction investigated as a primary hypothesis, potentially also exploring epigenetic mechanisms. More generally, studies of adverse health effects of air pollution may benefit from considering potential effect modification by diet and other factors. TRIAL REGISTRATION: Australia New Zealand Clinical Trial Registry. www.anzctr.org.au Registration: ACTRN12605000042640 , Date: 26th July 2005. Retrospectively registered, trial commenced prior to registry availability.


Assuntos
Alérgenos/efeitos adversos , Asma/fisiopatologia , Suplementos Nutricionais/análise , Exposição Ambiental , Óleos de Peixe/administração & dosagem , Poluição Relacionada com o Tráfego/efeitos adversos , Asma/induzido quimicamente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , New South Wales
2.
Ear Hear ; 38(1): 57-64, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27556525

RESUMO

OBJECTIVES: Combined vision and hearing impairment, termed dual sensory impairment (DSI), is associated with poorer health outcomes compared with a single sensory loss alone. Separate systems of care exist for visual and hearing impairment which potentially limit the effectiveness of managing DSI. To address this, a Hearing Screening Education Model (HSEM) was offered to older adults attending a low-vision clinic in Australia within this pilot study. The present study aimed to evaluate the benefits of seeking help on hearing handicap, self-perceived health, and use of community services among those identified with unmet hearing needs after participation in the HSEM. DESIGN: Of 210 older adults (>55 years of age) who completed the HSEM and were referred for follow-up, 169 returned for a follow-up interview at least 12 months later. Of these, 68 (40.2%) sought help, and the majority were seen by a hearing healthcare provider (89.7%). Changes in hearing handicap, quality of life, and reliance on community services between the baseline and 12-month follow-up were compared between those who sought help and those who did not. In addition, the perceived value of the HSEM was assessed. RESULTS: Results showed that there was no significant difference in hearing handicap between those who sought help (mean change -1.02 SD = 7.97, p = 0.3) and those who did not (mean change 0.94 SD = 7.68, p = 0.3), p = 0.18. The mental component of the SF-36 worsened significantly between baseline and follow-up measures across the whole group (mean change -2.49 SD = 9.98, p = 0.002). This was largely driven by those not seeking help, rather than those seeking help, but was not significantly different between the two groups. Those who sought help showed a significant reduction in the use of community services compared with those who did not. Further, all participants positively viewed the HSEM's underlying principle of greater integration between vision and hearing services. CONCLUSIONS: These findings suggest a need to further develop and evaluate integrated models of healthcare for older adults with DSI. It also highlights the importance of using broader measures of benefit, other than use of hearing aids to evaluate outcomes of hearing healthcare programs.


Assuntos
Serviços de Saúde Comunitária/organização & administração , Nível de Saúde , Perda Auditiva/diagnóstico , Comportamento de Busca de Ajuda , Educação de Pacientes como Assunto/organização & administração , Qualidade de Vida , Baixa Visão/complicações , Idoso , Idoso de 80 Anos ou mais , Austrália , Atenção à Saúde , Feminino , Seguimentos , Perda Auditiva/complicações , Perda Auditiva/reabilitação , Testes Auditivos , Humanos , Masculino , Programas de Rastreamento/organização & administração , Projetos Piloto
3.
Aust Health Rev ; 41(6): 672-679, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27809958

RESUMO

Objective The aim of the present study was to explore characteristics of interhospital transfers (IHT) and sharing of care among hospitals in New South Wales (NSW), Australia. Methods Data were extracted from patient-level linked hospital administrative datasets for separations from all NSW acute care hospitals from 1 July 2013 to 30 June 2015. Patient discharge and arrival information was used to identify IHTs. Characteristics of patients and related hospitals were then analysed. Results Transfer-in patients accounted for 3.9% of all NSW admitted patients and, overall, 7.3% of NSW admissions were associated with transfers (IHT rate). Patients with injuries and circulatory system diseases had the highest IHT rate, accounting for one-third of all IHTs. Patients were more often transferred to larger than smaller hospitals (61% vs 29%). Compared with private hospitals, public hospitals had a higher IHT rate (8.4% vs 5.1%) and a greater proportion of transfer-out IHTs (52% vs 28%). Larger public hospitals had lower IHT rates (3-8%) compared with smaller public hospitals (13-26%). Larger public hospitals received and retransferred higher proportions of IHT patients (52-58% and 11% respectively) than their smaller counterparts (26-30% and 2-3% respectively). Less than one-quarter of IHTs were between the public and private sectors or between government health regions. The number of interacting hospitals and their interactions varied across hospital peer groups. Conclusion NSW IHTs were often to hospitals with greater speciality services. The patterns of interhospital interactions could be affected by organisational and regional preferences. What is known about the topic? IHTs aim to provide efficient and effective care. Nonetheless, information on transfers and the sharing of care among hospitals in an Australian setting is lacking. Studies of transfers and hospital partnership patterns will inform efforts to improve patient-centred transfers and hospital accountability in terms of end outcomes for patients. What does this paper add? Transfer-in patients accounted for 3.9% of all NSW admissions; they were often (61%) transferred to hospitals with greater speciality services. The number of IHTs and sharing of care among hospitals varied across hospital peer groups, and could have been affected by organisational and regional preferences. What are the implications for practitioners? The findings of the present study suggest that different patterns of IHTs may not only have resulted from clinical priorities, but that organisational and regional preferences are also likely to be influential factors. Patient-centred IHTs and the development of guidelines need to be pursued to enhance the care and functionality of healthcare. Patient sharing should be acknowledged in hospital and regional performance profiling.


Assuntos
Hospitais/estatística & dados numéricos , Transferência de Pacientes/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Hospitais Especializados/organização & administração , Hospitais Especializados/estatística & dados numéricos , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , New South Wales , Transferência de Pacientes/organização & administração
4.
J Public Health (Oxf) ; 38(2): e1-4, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-26276549

RESUMO

BACKGROUND: Non-communicable diseases (NCDs) such as cardiovascular diseases (CVDs), cancer, lung disease and diabetes are major public health challenges for emerging economies. However, Masters of Public Health (MPH) curricula in the USA do not provide germane coursework. METHODS: To assess the availability of global NCD courses in MPH curricula, we searched the websites of the 50 schools accredited by the Council on Education for Public Health as of 1 July 2013. Our questionnaire queried availability of a global or international health department or track, availability of an NCD track, and the presence of courses on NCD, NCD risk factors, CVD or global NCDs as well as global health infrastructure. RESULTS: All schools had online course coursework available. Thirty-one schools (62%) offered a global/international health track or certificate; 38 (76%) offered an NCD course but only 4 (8%) offered a global NCD course. Of the schools with a global health program, none required an NCD course but all offered courses on global health economics or infrastructure. CONCLUSION: For public health schools to be aligned with global realities and to retain a leadership role, curricular initiatives that highlight the NCD epidemic and its societal complexities will need new emphasis.


Assuntos
Currículo , Saúde Global/educação , Doenças não Transmissíveis , Saúde Pública/educação , Currículo/normas , Humanos , Doenças não Transmissíveis/prevenção & controle , Faculdades de Saúde Pública/organização & administração , Faculdades de Saúde Pública/normas
5.
J Cardiovasc Nurs ; 31(1): 22-30, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-25419944

RESUMO

BACKGROUND: Chronic heart failure (CHF) is an increasing and costly health problem worldwide. Effective self-care behaviors reduce the cost and improve CHF outcomes. Interventions targeting improvement of self-care need to identify the baseline status of patients and factors associated with self-care to tailor the programs to patients' needs. AIM: The aim of this study was to describe self-care and its predictors in patients with CHF in western Iran. METHODS: In a cross-sectional study, 255 patients with CHF in Kermanshah were recruited and 231 (mean [SD] age, 66 [13] years; 51.5% women) completed the interviews. Self-care maintenance, self-care management, and self-care confidence were evaluated using a Persian heart failure self-care index. Each of these 3 measures had a total possible score of 100, with 22 indicators. RESULTS: The mean (SD) self-care scores were low: maintenance, 33.8 (10.7); management, 32.2 (12.0); and confidence, 43.6 (15.6). Self-care maintenance was significantly and positively associated with education, disease duration, and living conditions. Self-care management was significantly and positively associated with education and number of hospital admissions. However, the parameter estimates in all those relationships were small. CONCLUSION: Self-care in patients with CHF in Iran needs major improvement, and many determinants of self-care identified by other studies were not consistently associated with poor self-care scores in Iran. Further research considering a wide range of factors associated with self-care (eg, socioeconomic and health system-related factors) and application of culturally relevant interventional strategies is recommended.


Assuntos
Comportamentos Relacionados com a Saúde , Insuficiência Cardíaca/psicologia , Insuficiência Cardíaca/terapia , Autocuidado , Autoimagem , Idoso , Doença Crônica , Estudos Transversais , Feminino , Humanos , Irã (Geográfico) , Masculino , Pessoa de Meia-Idade , Fatores Socioeconômicos
6.
Med J Aust ; 203(1): 33-8, 2015 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-26126565

RESUMO

OBJECTIVE: To determine whether Care Navigation (CN), a nurse-led hospital-based coordinated care intervention, reduced the use of hospital services and improved quality of life for patients with chronic illness. DESIGN: Randomised controlled trial; participants were allocated to CN or standard care. PARTICIPANTS AND SETTING: Patients with chronic illness presenting to the emergency department of Nepean Hospital, Sydney, New South Wales. High-risk status for an unplanned admission was defined as i) three or more unplanned hospital admissions in 12 months for patients aged ≥ 70 or at least one admission for cardiac or respiratory disease in patients aged 16-69 years; or ii) judged by a CN nurse to be high risk and likely to benefit. MAIN OUTCOME MEASURES: Numbers of re-presentations or readmissions, quality of life, time to re-presentation, readmission or death, length of stay, and access to hospital and community health services. RESULTS: 500 participants were randomised between May 2010 and February 2011; 359 by previous unplanned admission and 141 by clinical impression. The CN group received more community health services (rate ratio, 1.94; 95% CI, 1.35-2.81; P < 0.001) than participants receiving standard care; however, this did not result in statistically significant differences in number of re-presentations (rate ratio, 0.83; 95% CI, 0.68-1.01; P = 0.07), number of readmissions (rate ratio, 0.85; 95% CI, 0.70-1.04; P = 0.11), quality of life at 24 months (mean difference, 0; 95% CI, - 0.10 to 0.09, P = 0.93), or other measures. CONCLUSIONS: CN did not improve quality of life or reduce unplanned hospital presentations or admissions despite community health services almost doubling. Future service development should explore potential benefits of linking navigated intrahospital care to ongoing, proactive care planning and delivery in the community. TRIAL REGISTRATION: ACTRN12609000554268.


Assuntos
Doença Crônica/enfermagem , Recursos Humanos de Enfermagem Hospitalar/organização & administração , Admissão do Paciente/estatística & dados numéricos , Navegação de Pacientes/organização & administração , Assistência Centrada no Paciente/organização & administração , Adolescente , Adulto , Idoso , Humanos , Pessoa de Meia-Idade , New South Wales , Avaliação de Resultados em Cuidados de Saúde , Avaliação de Programas e Projetos de Saúde , Adulto Jovem
7.
Health Promot Int ; 30(3): 595-605, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24399031

RESUMO

India is undergoing a shift in consumption from traditional foods to processed foods high in sugar, salt and fat. Partially hydrogenated vegetable oils (PHVOs) high in trans-fat are often used in processed foods in India given their low cost and extended shelf life. The World Health Organization has called for the elimination of PHVOs from the global food supply and recommends their replacement with polyunsaturated fat to maximize health benefits. This study examined barriers to replacing industrially produced trans-fat in the Indian food supply and systematically identified potential policy solutions to assist the government in encouraging its removal and replacement with healthier polyunsaturated fat. A combination of food supply chain analysis and semi-structured interviews with key stakeholders was conducted. The main barriers faced by the food-processing sector in terms of reducing use of trans-fat and replacing it with healthier oils in India were the low availability and high cost of oils high in polyunsaturated fats leading to a reliance on palm oil (high in saturated fat) and the low use of those healthier oils in product reformulation. Improved integration between farmers and processors, investment in technology and pricing strategies to incentivize use of healthier oils for product reformulation were identified as policy options. Food processors have trouble accessing sufficient affordable healthy oils for product reformulation, but existing incentives aimed at supporting food processing could be tweaked to ensure a greater supply of healthy oils with the potential to improve population health.


Assuntos
Gorduras na Dieta , Manipulação de Alimentos/economia , Manipulação de Alimentos/métodos , Abastecimento de Alimentos , Política Nutricional , Gorduras Insaturadas na Dieta , Humanos , Índia , Ácidos Graxos trans
8.
Ecol Food Nutr ; 54(6): 603-24, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25879914

RESUMO

The national Government of India has published draft regulation proposing a 5% upper limit of trans fat in partially hydrogenated vegetable oils (PHVOs). Global recommendations are to replace PHVOs with unsaturated fat but it is not known whether this will be feasible in India. We systematically identified policy options to address the three major underlying agricultural sector issues that influence reformulation with healthier oils: the low productivity of domestically produced oilseeds leading to a reliance on palm oil imports, supply chain wastage, and the low availability of oils high in unsaturated fats. Strengthening domestic supply chains in India will be necessary to maximize health gains associated with product reformulation.


Assuntos
Agricultura , Gorduras na Dieta , Abastecimento de Alimentos , Administração em Saúde Pública , Política Pública , Comércio , Produtos Agrícolas , Humanos , Índia , Fatores de Tempo
9.
Ear Hear ; 35(4): e153-61, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24852681

RESUMO

OBJECTIVES: The aims of this study were to investigate the potential unmet need for hearing services among older people attending low-vision rehabilitation, and pilot a "Hearing Screening and Education Model" (HSEM) of intervention to promote use of hearing services and aids among these individuals. DESIGN: In the Vision-Hearing project, 300 clients attending low-vision clinics in Sydney, Australia, participated in baseline interviews and the HSEM (2010-2011). The HSEM consisted of: (1) standard pure-tone audiometry; (2) discussion of hearing loss and implications of dual sensory impairment; and (3) provision of information on hearing services and facilitated referral. Those with hearing loss who did not own hearing aids, reported low use (<1 hr/day), or used a single aid with bilateral loss were referred for full assessment by an audiologist and to the follow-up arm of the study (n = 210). Follow-up interviews were conducted within 12 months to ascertain actions taken and audiological and other health outcomes. RESULTS: Of 169 participants in the follow-up study, 68 (40.2%) sought help for hearing loss within 12 months. Help-seekers had higher mean hearing handicap scores at baseline compared with non-help-seekers. The majority of help-seekers (85.3%) underwent a complete hearing assessment. Fifty-four percent (n = 37) were recommended hearing aids and the majority of these (n = 27) obtained new hearing aids. Seven participants had existing aids adjusted, and 3 obtained alternate assistive listening devices. Almost half of those receiving new aids or adjustments to hearing aids reported low use (<1 hr/day) at follow-up. Among help-seekers, 40% were unsure or did not believe their audiologist knew of their visual diagnosis. Of concern, 60% of participants did not seek help largely due to perceptions their hearing loss was not bad enough; the presence of competing priorities; concerns over dealing with vision loss and managing hearing aids with poor vision. CONCLUSIONS: Hearing- and vision-rehabilitation services need to better screen for, and take account of, dual sensory impairment among their older clients. If audiologists are made more aware of visual conditions affecting their clients, they may be better placed to facilitate access to appropriate technologies and rehabilitation, which may improve aid retention and benefit.


Assuntos
Acessibilidade aos Serviços de Saúde/organização & administração , Perda Auditiva/diagnóstico , Baixa Visão/reabilitação , Idoso , Idoso de 80 Anos ou mais , Audiometria de Tons Puros , Austrália , Feminino , Perda Auditiva/complicações , Perda Auditiva/reabilitação , Humanos , Masculino , Programas de Rastreamento , Avaliação das Necessidades/organização & administração , Educação de Pacientes como Assunto , Encaminhamento e Consulta/organização & administração , Baixa Visão/complicações
10.
J Cardiovasc Nurs ; 29(6): E1-5, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24434822

RESUMO

BACKGROUND: Chronic heart failure (CHF) is a common burdensome health problem worldwide. Self-care improves outcomes in patients with CHF. The Self-care of Heart Failure Index (SCHFI) is a well-known scale for assessing self-care. A reliable, valid, and culturally acceptable instrument is needed to develop and test self-care interventions in Iran. OBJECTIVE: We sought to translate and validate the Persian version of SCHFI v 6.2 (pSCHFI). METHODS AND RESULTS: We translated the SCHFI into Persian (pSCHFI) using standardized methods. The reliability was evaluated by assessing Cronbach's α coefficient. Expert opinion, discussion with patients, and confirmatory factor analysis were used to assess face validity, content validity, and construct validity, respectively. The analysis, using 184 participants, showed acceptable internal consistency and construct validity for the 3 subscales of pSCHFI-self-care maintenance, self-care management, and self-care self-confidence. CONCLUSION: The pSCHFI is a valid instrument with an acceptable reliability for evaluating self-care in Persian patients with heart failure.


Assuntos
Insuficiência Cardíaca/psicologia , Insuficiência Cardíaca/terapia , Idioma , Autocuidado , Inquéritos e Questionários , Traduções , Idoso , Análise Fatorial , Feminino , Insuficiência Cardíaca/diagnóstico , Humanos , Irã (Geográfico) , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Autoimagem
11.
Bull World Health Organ ; 91(4): 262-9H, 2013 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-23599549

RESUMO

OBJECTIVE: To systematically review evidence for the effectiveness of policies, including self-regulation, aimed at reducing industrially produced trans fatty acids (TFAs) in food. METHODS: The Medline, Embase and Cinahl databases were searched to identify peer-reviewed articles examining the effect of TFA policies. In addition, the first 20 pages of Google searches were examined for articles from the grey literature. A study was included if: (i) it was empirical and conducted in a "real-world" setting (i.e. modelling studies were excluded); (ii) it examined a TFA policy involving, for example, labelling, voluntary limits or bans; and (iii) it examined a policy's effect on TFA levels in food, people's diets, blood or breast milk. FINDINGS: Twenty-six articles met the inclusion criteria: 5 involved voluntary self-regulation; 8, labelling alone; 4, labelling and voluntary limits; 5, local bans and 4, national bans. Overall, the TFA content of food decreased with all types of policy intervention. In general, saturated fat levels increased or decreased, depending on the product type, and total fat content remained stable. National and local bans were most effective at eliminating TFAs from the food supply, whereas mandatory TFA labelling and voluntary TFA limits had a varying degree of success, which largely depended on food category. CONCLUSION: Policies aimed at restricting the TFA content of food were associated with significant reductions in TFA levels, without increasing total fat content. Such policies are feasible, achievable and likely to have an effect on public health.


Assuntos
Gorduras na Dieta/administração & dosagem , Política de Saúde/legislação & jurisprudência , Ácidos Graxos trans/administração & dosagem , Rotulagem de Alimentos/legislação & jurisprudência , Saúde Global , Humanos , Lipídeos/sangue , Leite Humano/química
12.
Med J Aust ; 199(7): 475-8, 2013 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-24099208

RESUMO

OBJECTIVE: To analyse the annual out-of-pocket (OOP) expenditure on health care as directly reported by Australian households grouped into older households (those with a reference person aged ≥ 65 years) and younger households (those with a reference person aged < 65 years). DESIGN: Descriptive analysis of statutory data collected by the Australian Bureau of Statistics. SETTING AND PARTICIPANTS: Probability sample of 9774 households across all states and territories. MAIN OUTCOME MEASURES: OOP expenditure on health care. RESULTS: The mean annual OOP expenditure on health care among the older households was estimated as $3585 ± $686 (9.4% of the total expenditure on all goods and services), and among the younger households, it was $3377 ± $83 (4.7% of the total expenditure on all goods and services). Cost of medicines (mainly non-prescription drugs and to a lesser extent the copayments for Pharmaceutical Benefits Scheme scripts) was the biggest item of expenditure for the older households, and the cost of private health insurance (PHI) was the most expensive item for the younger households. Overall, the OOP expenditure, as reported by the Australian households, was $28.7 ± $1.3 billion compared with $21.2 billion as reported by the Australian Institute of Health and Welfare. Unlike our estimate, the Institute's figure was based on statutory data collections and did not include the cost of PHI premiums. CONCLUSIONS: OOP expenses account for almost a quarter (22%) of the total health care costs in Australia. The mean annual OOP expenditure was slightly higher for the older households compared with the younger households, despite the fact that the older households had significantly lower income and had greater access to health care cards, which were used to defray additional health care costs associated with age.


Assuntos
Financiamento Pessoal/estatística & dados numéricos , Custos de Cuidados de Saúde/estatística & dados numéricos , Fatores Etários , Idoso , Austrália , Atenção à Saúde/economia , Custos de Medicamentos/estatística & dados numéricos , Características da Família , Gastos em Saúde/estatística & dados numéricos , Humanos , Renda/estatística & dados numéricos , Seguro Saúde/economia , Seguro Saúde/estatística & dados numéricos , Pessoa de Meia-Idade
13.
Public Health Nutr ; 16(12): 2273-80, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23164094

RESUMO

OBJECTIVE: India has proposed legislating an upper limit of trans fat in partially hydrogenated vegetable oils and mandating trans fat labelling in an effort to reduce intakes. The objective of the present study was to examine the complexities of regulating trans fat in India by examining the policy processes involved and the perceived implementation challenges. DESIGN: Semi-structured interviews (n 18) were conducted with key informants from various sectors. Interviewees were asked about sources of trans fat in the food supply, existing policies that may influence trans fats and perceived challenges related to the proposed trans fat regulation, in addition to questions tailored to their area of expertise. Interview data were organised based on common themes. SETTING: Interviews were conducted in India. SUBJECTS: Interviewees were key informants from various sectors including agriculture, trade, industry and health. RESULTS: Several themes were identified related to the complexity of regulating trans fat in India. A lack of trans fat awareness, the large unorganised retail sector, a need for suitable alternative products that are both acceptable to consumers and affordable, and a need to build capacity were crucial factors affecting India's ability to successfully regulate trans fat. The limited number of food inspectors will create an additional challenge in terms of enforcement of trans fat regulation. CONCLUSIONS: Although India will face challenges in regulating trans fat, legislating an upper limit of trans fat in partially hydrogenated vegetable oils will likely be the most effective approach to reducing it in the food supply. Ongoing engagement with industry, agriculture, trade and processing sectors will prove essential in terms of product reformulation.


Assuntos
Dieta , Gorduras na Dieta , Rotulagem de Alimentos/legislação & jurisprudência , Abastecimento de Alimentos/legislação & jurisprudência , Política Nutricional , Ácidos Graxos trans , Conscientização , Comércio , Comportamento do Consumidor , Dinamarca , Preferências Alimentares , Humanos , Índia , Entrevistas como Assunto
14.
Aust Health Rev ; 37(1): 19-25, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23158955

RESUMO

INTRODUCTION: The Australian federal government is developing a policy response to chronic disease in Australia. The Serious and Continuing Illness Policy and Practice Study examined the experience of individuals with chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD) or type 2 diabetes mellitus (diabetes) in the Australian Capital Territory (ACT) and Western Sydney. This paper describes the disease-specific experiences of people interviewed. METHODS: We conducted semi-structured interviews with 40 individuals aged 45-85 years with CHF, COPD or diabetes in 2008. Interviews were recorded and transcribed. Qualitative content analysis was performed, assisted by QSR Nvivo 8 qualitative data software. RESULTS: Participants with CHF (n=9) came to terms with the prospect of unpredictable sudden death. Participants with COPD (n=15) were angry about limitations it imposed on their lives. Participants with diabetes (n=16) experienced a steep learning curve in self-management of their condition surrounded by high levels of uncertainty. CONCLUSION: Although people with chronic illness share many experiences, a person's overall experience of living with chronic illness is significantly shaped by the nature of their specific dominant disease. Policies for patient-centred care must take account of both generic and disease-specific elements.


Assuntos
Diabetes Mellitus Tipo 2/psicologia , Política de Saúde , Insuficiência Cardíaca/psicologia , Assistência Centrada no Paciente/normas , Doença Pulmonar Obstrutiva Crônica/psicologia , Adaptação Psicológica , Idoso , Idoso de 80 Anos ou mais , Território da Capital Australiana , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , New South Wales , Pesquisa Qualitativa
15.
Lancet ; 378(9795): 1006-14, 2011 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-21907864

RESUMO

BACKGROUND: We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms underlying the disease. METHODS: We did a genome-wide association study (GWAS) in 2669 physician-diagnosed asthmatics and 4528 controls from Australia. Seven loci were prioritised for replication after combining our results with those from the GABRIEL consortium (n=26,475), and these were tested in an additional 25,358 independent samples from four in-silico cohorts. Quantitative multi-marker scores of genetic load were constructed on the basis of results from the GABRIEL study and tested for association with asthma in our Australian GWAS dataset. FINDINGS: Two loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP). The 11q13.5 locus was significantly associated with atopic status among asthmatics (OR 1·33, p=7×10(-4)), suggesting that it is a risk factor for allergic but not non-allergic asthma. Multi-marker association results are consistent with a highly polygenic contribution to asthma risk, including loci with weak effects that might be shared with other immune-related diseases, such as NDFIP1, HLA-B, LPP, and BACH2. INTERPRETATION: The IL6R association further supports the hypothesis that cytokine signalling dysregulation affects asthma risk, and raises the possibility that an IL6R antagonist (tocilizumab) may be effective to treat the disease, perhaps in a genotype-dependent manner. Results for the 11q13.5 locus suggest that it directly increases the risk of allergic sensitisation which, in turn, increases the risk of subsequent development of asthma. Larger or more functionally focused studies are needed to characterise the many loci with modest effects that remain to be identified for asthma. FUNDING: National Health and Medical Research Council of Australia. A full list of funding sources is provided in the webappendix.


Assuntos
Asma/genética , Cromossomos Humanos Par 11/genética , Loci Gênicos/genética , Proteínas de Membrana/genética , Polimorfismo de Nucleotídeo Único , Receptores de Interleucina-6/genética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Asma/imunologia , Criança , Pré-Escolar , Feminino , Predisposição Genética para Doença/genética , Estudo de Associação Genômica Ampla , Humanos , Hipersensibilidade Imediata/genética , Desequilíbrio de Ligação , Masculino , Pessoa de Meia-Idade , Adulto Jovem
16.
J Neurol Neurosurg Psychiatry ; 83(2): 138-45, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22019549

RESUMO

BACKGROUND: Cerebrovascular disease (stroke) is the second most common cause of death and among the top five causes of morbidity in many developed and developing countries. The aim of this study was to investigate patterns of increase and decrease in stroke mortality in 48 different countries. METHODS: The mortality curves of stroke for 48 countries that had reliable data and met other selection criteria were examined using age standardised death rates for 35-74 years from the WHO. Annual mortality rates for individual countries from 1950 to 2005 were plotted and a table and graph were used to classify countries by magnitude, pattern and timing of stroke mortality. Male and female trends were plotted separately. RESULTS: The secular trend of stroke mortality varied markedly among countries. Different stroke patterns were distinguishable, including 'declining', 'rise and fall', 'rising' and 'flat'. Furthermore, epidemic peaks per 10(5) (M/F) were higher in Asia, in particular in Japan (433/304), Russian Federation (388/221) and Bulgaria (301/214), and were lowest in Canada and Australia (29/18). There were considerable differences among some continental and regional geographic areas. For example, Japan, Belgium, Portugal and Eastern Europe exhibited a rise and fall pattern while other countries fell into the other three categories. CONCLUSIONS: In many countries, stroke mortality has decreased, between 1950 and 2005, often very considerably. The different dates of mortality downturn likely are consistent with the implementation of various prevention strategies. This could be translated to policy interventions for stroke control in countries with a rising trend of the disease.


Assuntos
Transtornos Cerebrovasculares/mortalidade , Adulto , Idoso , América Central/epidemiologia , Atestado de Óbito , Feminino , Humanos , Classificação Internacional de Doenças , Masculino , Pessoa de Meia-Idade , América do Norte/epidemiologia , Análise de Regressão , Fatores de Risco , Fatores Sexuais , América do Sul/epidemiologia , Acidente Vascular Cerebral/mortalidade , População Branca , Organização Mundial da Saúde
18.
Age Ageing ; 41(2): 195-200, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22130560

RESUMO

BACKGROUND: age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS: a total of 1,952 Blue Mountains Hearing Study participants aged ≥60 years had their hearing levels measured using pure-tone audiometry. A survey instrument with questions on functional status as determined by the Older Americans Resources and Services ADL scale was administered. RESULTS: one hundred and sixty-four (10.4%) participants reported ADL difficulty. A higher proportion of hearing impaired than non-impaired adults reported difficulties in performing three out of the seven basic ADL and six out of the seven instrumental ADL tasks. After multivariable adjustment, increased severity of hearing loss was associated with impaired ADL (P(trend )= 0.001). Subjects with moderate to severe hearing loss compared with those without, had a 2.9-fold increased likelihood of reporting difficulty in ADL, multivariate-adjusted odds ratio (OR): 2.87 [95% confidence interval (CI): 1.59-5.19]. Participants aged <75 years with hearing loss compared with those without, had 2-fold higher odds of impaired ADL. Having worn or wearing a hearing aid was also associated with a 2-fold increased likelihood of impaired ADL. CONCLUSION: functional status as measured by a common ADL scale is diminished in older hearing impaired adults. Our findings suggest that severely diminished hearing could make the difference between independence and the need for formal support services or placement.


Assuntos
Atividades Cotidianas , Envelhecimento , Avaliação da Deficiência , Avaliação Geriátrica , Pessoas com Deficiência Auditiva , Presbiacusia/diagnóstico , Estimulação Acústica , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Audiometria de Tons Puros , Limiar Auditivo , Correção de Deficiência Auditiva , Estudos Transversais , Feminino , Auxiliares de Audição , Humanos , Vida Independente , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , New South Wales , Razão de Chances , Pessoas com Deficiência Auditiva/psicologia , Pessoas com Deficiência Auditiva/reabilitação , Presbiacusia/fisiopatologia , Presbiacusia/psicologia , Presbiacusia/reabilitação , Medição de Risco , Fatores de Risco , Índice de Gravidade de Doença , Inquéritos e Questionários
19.
Age Ageing ; 41(5): 618-23, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22591986

RESUMO

BACKGROUND: we aimed to assess both cross-sectional and temporal links between measured hearing impairment and self-perceived hearing handicap, and health outcomes. METHODS: in total, 811 Blue Mountains Hearing Study participants (Sydney, Australia) aged ≥55 years were examined twice (1997-99 and 2002-04). Hearing levels were measured with pure-tone audiometry. The shortened version of the hearing handicap inventory (HHIE-S) was administered, scores ≥8 defined hearing handicap. RESULTS: baseline hearing impairment was strongly associated with 7 of the 10 HHIE-S questions, 5 years later. Individuals with and without hearing impairment at baseline reported that they felt embarrassed and/or frustrated by their hearing problem, and that it hampered their personal/social life, multivariable-adjusted OR: 11.5 (CI: 3.5-38.1), OR: 6.3 (CI: 2.5-15.7) and OR: 6.0 (CI: 2.1-17.5), respectively, 5 years later. Hearing-impaired, compared with non-hearing-impaired adults had a significantly higher risk of developing moderate or severe hearing handicap, OR: 3.35 (CI: 1.91-5.90) and OR: 6.60 (CI: 1.45-30.00), respectively. Cross-sectionally (at wave 2), hearing handicap increased the odds of depressive symptoms and low self-rated health by 80 and 46%, respectively. CONCLUSION: older, hearing-impaired adults were significantly more likely to experience emotional distress and social engagement restrictions (self-perceived hearing handicap) directly due to their hearing impairment.


Assuntos
Pessoas com Deficiência Auditiva/psicologia , Autoimagem , Discriminação Social/psicologia , Estresse Psicológico/epidemiologia , Estresse Psicológico/psicologia , Idoso , Idoso de 80 Anos ou mais , Austrália , Estudos Transversais , Feminino , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Qualidade de Vida/psicologia , Estudos Retrospectivos , Fatores de Risco , Inquéritos e Questionários
20.
Am J Public Health ; 101(8): 1386-90, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21680924

RESUMO

A confluence of stimuli is propelling academic public health to embrace the prevention of chronic disease in developing countries as its new frontier. These stimuli are a growing recognition of the epidemic, academia's call to reestablish public health as a mover of societal tectonics rather than a handmaiden to medicine's focus on the individual, and the turmoil in the US health system that makes change permissible. To enable graduating professionals to participate in the assault on chronic diseases, schools of public health must allocate budgets and other resources to this effort. The barriers to chronic disease prevention and risk factor modulation are cultural and political; confronting them will require public health to work with a wide variety of disciplines. Chronic disease will likely become the dominant global public health issue soon. In addressing this issue, academia needs to lead, not follow.


Assuntos
Doença Crônica/prevenção & controle , Países em Desenvolvimento , Prática de Saúde Pública , Faculdades de Saúde Pública , Doenças Cardiovasculares/prevenção & controle , Atenção à Saúde/organização & administração , Economia , Saúde Global , Órgãos Governamentais , Política de Saúde , Humanos , Formulação de Políticas , Saúde Pública/educação , Comportamento de Redução do Risco , Mudança Social
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