Detalhe da pesquisa
1.
Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice.
Int J Mol Sci
; 24(16)2023 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628730
2.
Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease.
Neurobiol Dis
; 159: 105481, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411703
3.
Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.
Biochim Biophys Acta Mol Basis Dis
; 1864(1): 152-161, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29038051
4.
The Role of APOE and TREM2 in Alzheimer's Disease-Current Understanding and Perspectives.
Int J Mol Sci
; 20(1)2018 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587772
5.
Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury.
Neurobiol Dis
; 105: 1-14, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28502803
6.
Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.
J Neurosci
; 35(34): 11862-76, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26311769
7.
Opposing effects of Apoe/Apoa1 double deletion on amyloid-ß pathology and cognitive performance in APP mice.
Brain
; 138(Pt 12): 3699-715, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26510953
8.
RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.
Neurobiol Dis
; 82: 132-140, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26071899
9.
ATP-binding cassette transporter A1: from metabolism to neurodegeneration.
Neurobiol Dis
; 72 Pt A: 13-21, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844148
10.
Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration.
Neurobiol Dis
; 63: 107-14, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24269917
11.
Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
J Neurosci
; 32(38): 13125-36, 2012 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993429
12.
APOEε4 and risk of Alzheimer's disease - time to move forward.
Front Neurosci
; 17: 1195724, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37274212
13.
Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer's disease model mice.
Cell Rep
; 42(7): 112785, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37436901
14.
Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice.
Toxicol Rep
; 9: 393-403, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35299870
15.
Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.
J Neurosci
; 30(20): 6862-72, 2010 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20484628
16.
Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice.
J Biol Chem
; 285(47): 36945-57, 2010 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20739292
17.
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration.
Biochim Biophys Acta
; 1801(8): 824-30, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188211
18.
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Nat Commun
; 12(1): 3416, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099706
19.
Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles.
Nat Aging
; 1(12): 1148-1161, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665306
20.
Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
Mol Neurodegener
; 15(1): 41, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703241