Detalhe da pesquisa
1.
Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline.
Nucleic Acids Res
; 52(6): 2836-2847, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38412249
2.
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif.
Nucleic Acids Res
; 51(15): 7736-7748, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439359
3.
Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability.
Chemistry
; : e202401254, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687344
4.
Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents.
Angew Chem Int Ed Engl
; 62(34): e202304476, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37218580
5.
Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication.
Molecules
; 27(3)2022 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164317
6.
Stable Hairpin Structures Formed by Xylose-Based Nucleic Acids.
Chembiochem
; 22(9): 1638-1645, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33427360
7.
Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.
Nucleic Acids Res
; 47(13): 7130-7142, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31334814
8.
An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1.
J Biol Chem
; 294(19): 7878-7891, 2019 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30923126
9.
Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors.
FASEB J
; 33(3): 3693-3703, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509130
10.
Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase.
Bioorg Med Chem
; 28(15): 115580, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631562
11.
Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Molecules
; 25(20)2020 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33081246
12.
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI.
Angew Chem Int Ed Engl
; 59(26): 10549-10556, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32208550
13.
Synthesis and Conformation of Pentopyranoside Nucleoside Phosphonates.
J Org Chem
; 84(11): 6589-6603, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31046278
14.
N8-Glycosylated 8-Azapurine and Methylated Purine Nucleobases: Synthesis and Study of Base Pairing Properties.
J Org Chem
; 84(21): 13394-13409, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31617362
15.
Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies.
Molecules
; 24(3)2019 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30696094
16.
Methylated Nucleobases: Synthesis and Evaluation for Base Pairing Inâ Vitro and Inâ Vivo.
Chemistry
; 24(48): 12695-12707, 2018 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29883012
17.
Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening.
Int J Mol Sci
; 19(11)2018 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463319
18.
Phage Display-Directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication.
Mol Ther
; 29(2): 887, 2021 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33385332
19.
Xylonucleic acid: synthesis, structure, and orthogonal pairing properties.
Nucleic Acids Res
; 43(15): 7189-200, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26175047
20.
Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.
Nucleic Acids Res
; 47(22): 11976-11977, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31713624