Detalhe da pesquisa
1.
Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma.
J Biol Chem
; 298(10): 102434, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041632
2.
Mechanistic insights into the activation of ester prodrugs of 666-15.
Bioorg Med Chem Lett
; 30(19): 127455, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730943
3.
Design, synthesis and evaluation of antitumor acylated monoaminopyrroloquinazolines.
Bioorg Med Chem Lett
; 27(14): 3107-3110, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28552339
4.
Design, synthesis and biological evaluation of regioisomers of 666-15 as inhibitors of CREB-mediated gene transcription.
Bioorg Med Chem Lett
; 27(4): 994-998, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28073675
5.
Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription.
Bioorg Med Chem Lett
; 23(19): 5371-5, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23953193
6.
CG -SLENP: A chemical genetics strategy to selectively label existing proteins and newly synthesized proteins.
bioRxiv
; 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961390
7.
Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors.
J Cell Biol
; 177(4): 659-69, 2007 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17517962
8.
Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription.
Bioorg Med Chem
; 20(23): 6811-20, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23102993
9.
Design, Synthesis and Biological Evaluation of Prodrugs of 666-15 as Inhibitors of CREB-Mediated Gene Transcription.
ACS Med Chem Lett
; 13(3): 388-395, 2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35300089
10.
A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target.
Acta Pharm Sin B
; 12(5): 2406-2416, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35646545
11.
Calcium-activated Myosin V closes the Drosophila pupil.
Curr Biol
; 18(13): 951-5, 2008 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18585038
12.
A suite of bioassays to evaluate CREB inhibitors.
Methods Enzymol
; 633: 169-184, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046844
13.
Identification of lamins as the molecular targets of LBL1 using a clickable photoaffinity probe.
Methods Enzymol
; 633: 185-201, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046845
14.
Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15.
J Med Chem
; 62(24): 11423-11429, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31765143
15.
Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics.
Front Mol Biosci
; 5: 35, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29732373
16.
A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks.
ACS Cent Sci
; 4(9): 1201-1210, 2018 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30276254
17.
Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins.
ACS Chem Biol
; 13(5): 1380-1387, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29648791
18.
Systemic Inhibition of CREB is Well-tolerated in vivo.
Sci Rep
; 6: 34513, 2016 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694829
19.
The chemistry and pharmacology of privileged pyrroloquinazolines.
Medchemcomm
; 6(4): 510-520, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937878
20.
Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.
J Med Chem
; 58(12): 5075-87, 2015 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26023867