Detalhe da pesquisa
1.
BET Bromodomain Inhibitors: Novel Design Strategies and Therapeutic Applications.
Molecules
; 28(7)2023 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37049806
2.
Constitutively Active Androgen Receptor in Hepatocellular Carcinoma.
Int J Mol Sci
; 23(22)2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430245
3.
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-2.
Bioconjug Chem
; 32(1): 215-223, 2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356169
4.
Mechanistic Insights into the Allosteric Inhibition of Androgen Receptors by Binding Function 3 Antagonists from an Integrated Molecular Modeling Study.
J Chem Inf Model
; 61(7): 3477-3494, 2021 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165949
5.
Novel pyrrolopyrimidines as Mps1/TTK kinase inhibitors for breast cancer.
Bioorg Med Chem
; 25(7): 2156-2166, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28259529
6.
Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury.
Am J Physiol Lung Cell Mol Physiol
; 311(5): L868-L880, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638904
7.
Niclosamide Analogs for Treatment of Ovarian Cancer.
Int J Gynecol Cancer
; 25(8): 1377-85, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186072
8.
Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.
Biochem J
; 450(3): 547-57, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23301618
9.
Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones.
Bioorg Med Chem Lett
; 23(24): 6864-7, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24176397
10.
Design, synthesis and biological studies of novel tubulin inhibitors.
Bioorg Med Chem Lett
; 23(15): 4465-8, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23790539
11.
Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle.
Bioorg Med Chem Lett
; 23(19): 5429-33, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23968825
12.
Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action.
Bioorg Med Chem Lett
; 23(24): 6902-4, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24169233
13.
Anticancer activity and SAR studies of substituted 1,4-naphthoquinones.
Bioorg Med Chem
; 21(15): 4662-9, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23791367
14.
A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
Int J Cancer
; 130(6): 1459-69, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21520044
15.
Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
Invest New Drugs
; 30(3): 916-26, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21340507
16.
Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase.
J Enzyme Inhib Med Chem
; 27(4): 476-89, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21864033
17.
Computational modeling studies reveal the origin of the binding preference of 3-(3,4-di hydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids for AKR1C3 over its isoforms.
Protein Sci
; 31(12): e4499, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36335585
18.
Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells.
J Biol Chem
; 285(35): 27429-27439, 2010 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20562100
19.
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines.
BMC Cancer
; 11: 112, 2011 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21443800
20.
Development of Murine Leukemia Virus Integrase-Derived Peptides That Bind Brd4 Extra-Terminal Domain as Candidates for Suppression of Acute Myeloid Leukemia.
ACS Pharmacol Transl Sci
; 4(5): 1628-1638, 2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661079