Detalhe da pesquisa
1.
The molecular basis and disease relevance of non-homologous DNA end joining.
Nat Rev Mol Cell Biol
; 21(12): 765-781, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077885
2.
Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Nat Rev Mol Cell Biol
; 18(8): 495-506, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512351
3.
The RNA tether model for human chromosomal translocation fragile zones.
Trends Biochem Sci
; 49(5): 391-400, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490833
4.
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
Nat Immunol
; 16(7): 766-774, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25985233
5.
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Annu Rev Biochem
; 79: 181-211, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20192759
6.
AID and Reactive Oxygen Species Can Induce DNA Breaks within Human Chromosomal Translocation Fragile Zones.
Mol Cell
; 68(5): 901-912.e3, 2017 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29220655
7.
The mechanisms of human lymphoid chromosomal translocations and their medical relevance.
Crit Rev Biochem Mol Biol
; 57(3): 227-243, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34875186
8.
RNA Polymerase Collision versus DNA Structural Distortion: Twists and Turns Can Cause Break Failure.
Mol Cell
; 62(3): 327-334, 2016 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153532
9.
Structural analysis of the basal state of the Artemis:DNA-PKcs complex.
Nucleic Acids Res
; 50(13): 7697-7720, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35801871
10.
Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturation and permits antibody optimization.
Nucleic Acids Res
; 50(20): 11738-11754, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36321646
11.
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity.
Cell
; 135(6): 1130-42, 2008 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19070581
12.
Concept of DNA Lesion Longevity and Chromosomal Translocations.
Trends Biochem Sci
; 43(7): 490-498, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735400
13.
Transposons to V(D)J Recombination: Evolution of the RAG Reaction.
Trends Immunol
; 40(8): 668-670, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31307890
14.
AID and Reactive Oxygen Species Can Induce DNA Breaks within Human Chromosomal Translocation Fragile Zones.
Mol Cell
; 73(3): 639, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735656
15.
Polymerase µ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system.
Nucleic Acids Res
; 48(7): 3605-3618, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32052035
16.
NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV.
Nucleic Acids Res
; 48(22): 12746-12750, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264406
17.
Current insights into the mechanism of mammalian immunoglobulin class switch recombination.
Crit Rev Biochem Mol Biol
; 54(4): 333-351, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31509023
18.
Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features.
J Biol Chem
; 295(35): 12368-12377, 2020 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32576658
19.
Structural evidence for an in trans base selection mechanism involving Loop1 in polymerase µ at an NHEJ double-strand break junction.
J Biol Chem
; 294(27): 10579-10595, 2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138645
20.
Turning anti-ageing genes against cancer.
Nat Rev Mol Cell Biol
; 9(11): 903-10, 2008 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18946478