Detalhe da pesquisa
1.
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.
Nature
; 520(7548): 549-52, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707806
2.
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real-life analysis of three larger gene panels.
Int J Cancer
; 144(9): 2303-2312, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446996
3.
Size matters: Dissecting key parameters for panel-based tumor mutational burden analysis.
Int J Cancer
; 144(4): 848-858, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30238975
4.
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases.
Int J Cancer
; 145(3): 649-661, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653256
5.
Precision oncology based on omics data: The NCT Heidelberg experience.
Int J Cancer
; 141(5): 877-886, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28597939
6.
Preferred co-localization of chromosome 8 and 21 in myeloid bone marrow cells detected by three dimensional molecular cytogenetics.
Int J Mol Med
; 24(3): 335-41, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19639225
7.
Implementing tumor mutational burden (TMB) analysis in routine diagnostics-a primer for molecular pathologists and clinicians.
Transl Lung Cancer Res
; 7(6): 703-715, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30505715
8.
Targeted molecular profiling reveals genetic heterogeneity of poromas and porocarcinomas.
Pathology
; 50(3): 327-332, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269125
9.
Validating Comprehensive Next-Generation Sequencing Results for Precision Oncology: The NCT/DKTK Molecularly Aided Stratification for Tumor Eradication Research Experience.
JCO Precis Oncol
; 2: 1-13, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135162
10.
PD-L1 (CD274) copy number gain, expression, and immune cell infiltration as candidate predictors for response to immune checkpoint inhibitors in soft-tissue sarcoma.
Oncoimmunology
; 6(3): e1279777, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28405504
11.
The Fanconi anemia pathway is required for efficient repair of stress-induced DNA damage in haematopoietic stem cells.
Cell Cycle
; 14(17): 2734-42, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178207
12.
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cell Stem Cell
; 15(4): 507-522, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25158935
13.
Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.
Cell Stem Cell
; 14(6): 824-37, 2014 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24704494
14.
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Genome Med
; 6(4): 34, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24944583
15.
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Cell Cycle
; 13(22): 3476-87, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25483069
16.
Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.
Anemia
; 2012: 265790, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22675615