Detalhe da pesquisa
1.
Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat Immunol
; 25(6): 1073-1082, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38816615
2.
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity
; 55(11): 2149-2167.e9, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179689
3.
Long-primed germinal centres with enduring affinity maturation and clonal migration.
Nature
; 609(7929): 998-1004, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36131022
4.
Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors.
EMBO J
; 40(2): e105926, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33258500
5.
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration.
Nature
; 614(7949): E43, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36717721
6.
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
Proc Natl Acad Sci U S A
; 117(37): 22920-22931, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873644
7.
Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.
Mol Ther
; 27(12): 2080-2090, 2019 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515132
8.
Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA.
PLoS Pathog
; 12(4): e1005557, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27105075
9.
Exploiting chimeric human antibodies to characterize a protective epitope of Neisseria adhesin A, one of the Bexsero vaccine components.
FASEB J
; 30(1): 93-101, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26304221
10.
Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody.
Proc Natl Acad Sci U S A
; 111(48): 17128-33, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25404323
11.
A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo.
J Cell Mol Med
; 19(5): 1122-32, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25721149
12.
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models.
Sci Immunol
; 9(95): eadn0622, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753808
13.
mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Science
; 384(6697): eadk0582, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753770
14.
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
Sci Transl Med
; 16(748): eadn0223, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753806
15.
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science
; 384(6697): eadj8321, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753769
16.
Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer.
Cell Rep
; 38(10): 110485, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263576
17.
Vaccination induces HIV broadly neutralizing antibody precursors in humans.
Science
; 378(6623): eadd6502, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454825
18.
Post-neoadjuvant strategies in breast cancer: From risk assessment to treatment escalation.
Cancer Treat Rev
; 72: 7-14, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30414986
19.
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers.
Science
; 363(6427): 649-654, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573546
20.
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science
; 366(6470)2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31672916