Detalhe da pesquisa
1.
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
Arch Toxicol
; 94(7): 2435-2461, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32632539
2.
Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq.
Arch Toxicol
; 92(8): 2517-2531, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30008028
3.
Adverse outcome pathways: opportunities, limitations and open questions.
Arch Toxicol
; 91(11): 3477-3505, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29051992
4.
Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline.
J Biol Chem
; 290(31): 19121-32, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055719
5.
"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.
Arch Toxicol
; 90(6): 1529-1539, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27129694
6.
Interleukin-19 as a translational indicator of renal injury.
Arch Toxicol
; 89(1): 101-6, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24714768
7.
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel.
Toxicol Appl Pharmacol
; 279(2): 163-72, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24907557
8.
An overview of transcriptional regulation in response to toxicological insult.
Arch Toxicol
; 87(1): 49-72, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22926699
9.
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model.
Arch Toxicol
; 86(4): 571-89, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22124623
10.
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.
Arch Toxicol
; 86(11): 1741-51, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22760423
11.
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
Toxicol In Vitro
; 79: 105269, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757180
12.
Mid-gestation low-dose LPS administration results in female-specific excessive weight gain upon a western style diet in mouse offspring.
Sci Rep
; 10(1): 19618, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184349
13.
Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.
Front Genet
; 10: 517, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31231426
14.
Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.
Front Genet
; 9: 429, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333853
15.
Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens.
Front Genet
; 9: 558, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559759
16.
Improving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry.
Anal Chim Acta
; 930: 13-22, 2016 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27265900
17.
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study.
Toxicol In Vitro
; 30(1 Pt A): 106-16, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450743
18.
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics.
Toxicol In Vitro
; 30(1 Pt A): 117-27, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450742
19.
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
Toxicol In Vitro
; 30(1 Pt A): 7-18, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25596134
20.
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.
Toxicol In Vitro
; 30(1 Pt A): 128-37, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25536518