Detalhe da pesquisa
1.
IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling.
Nat Immunol
; 19(4): 354-365, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563620
2.
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
Nat Immunol
; 14(1): 72-81, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23202271
3.
Mechanisms of Corticosteroid Resistance in Type 17 Asthma.
J Immunol
; 209(10): 1860-1869, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36426949
4.
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF).
Nat Immunol
; 12(9): 853-60, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822258
5.
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Nat Immunol
; 12(9): 844-52, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822257
6.
STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis.
J Neuroinflammation
; 18(1): 98, 2021 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879167
7.
IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility.
J Immunol
; 202(5): 1540-1548, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683702
8.
TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation.
Proc Natl Acad Sci U S A
; 115(45): 11531-11536, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352854
9.
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis.
Immunity
; 32(3): 414-25, 2010 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20303295
10.
IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.
J Immunol
; 199(11): 3849-3857, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070673
11.
Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency.
Proc Natl Acad Sci U S A
; 113(51): E8277-E8285, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27930337
12.
Crystal structure of IL-17 receptor B SEFIR domain.
J Immunol
; 190(5): 2320-6, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23355738
13.
HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization.
J Immunol
; 191(2): 640-9, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23772036
14.
Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 5): 1476-83, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816115
15.
Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes.
J Immunol
; 189(1): 33-7, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22649194
16.
A TH17-intrinsic IL-1ß-STAT5 axis drives steroid resistance in autoimmune neuroinflammation.
Sci Immunol
; 9(95): eabq1558, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38701190
17.
LRIG1 engages ligand VISTA and impairs tumor-specific CD8+ T cell responses.
Sci Immunol
; 9(95): eadi7418, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38758807
18.
T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation.
J Immunol
; 187(6): 3155-64, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856933
19.
TRAF4 is crucial for the propagation of ST2+ memory Th2 cells in IL-33-mediated type 2 airway inflammation.
bioRxiv
; 2023 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798382
20.
TRAF4 is crucial for ST2+ memory Th2 cell expansion in IL-33-driven airway inflammation.
JCI Insight
; 8(18)2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607012