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Chin Med J (Engl) ; 125(17): 3133-6, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22932194

RESUMO

BACKGROUND: The correlation between the plasma D-dimer level and deep vein thrombosis has not been conclusive in various studies. The aim of this research was to study the relationship between plasma D-dimer levels and the severity of orthopedic trauma by retrospective examination of orthopedic trauma cases. METHODS: Clinically acute trauma and non-acute trauma patients were selected and their plasma D-dimer levels were measured. Plasma D-dimer levels in patients of these two groups were compared. The relationship between the plasma D-dimer level and the severity of the trauma was also studied. RESULTS: There were 548 cases in the acute trauma group and 501 cases in the non-acute trauma group. The levels of plasma D-dimer were significantly higher in the acute trauma group than in the non-acute trauma group (P < 0.01). In the acute trauma group, the correlation between the D-dimer level and the number of fractures was a positive linear correlation (r = 0.9532). CONCLUSIONS: Elevated plasma D-dimer is common in trauma patients. The D-dimer level and the number of fractures in the trauma patients are closely correlated. D-dimer is not only an indicator for the diagnosis of deep vein thrombosis and pulmonary embolus, but also an indicator of the severity of trauma in acute trauma patients.


Assuntos
Produtos de Degradação da Fibrina e do Fibrinogênio/análise , Ferimentos e Lesões/sangue , Doença Aguda , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Embolia Pulmonar/sangue , Estudos Retrospectivos , Índice de Gravidade de Doença , Trombose Venosa/sangue
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