1.
Zh Nevropatol Psikhiatr Im S S Korsakova
; 86(2): 187-90, 1986.
Artigo
em Russo
| MEDLINE
| ID: mdl-3518311
RESUMO
The authors examined 58 patients with multiple sclerosis and 56 healthy donors. The patients presented elevated production of the migration inhibition factor (MIF) by lymphoid cells to cerebral tissue antigens, most expressed in the acute period of the disease. The blood serum of patients with multiple sclerosis showed inhibitory activity, lymphocytes spontaneously produced the MIF in vitro. Hyperproduction of lymphokins may serve as one of the pathogenetic factors of generalization of the inflammatory process in the central nervous system in patients with multiple sclerosis and indicates impaired regulation of immunity.
Assuntos
Encéfalo/imunologia , Fatores Inibidores da Migração de Leucócitos/sangue , Leucócitos/imunologia , Linfocinas/sangue , Esclerose Múltipla/imunologia , Movimento Celular , Feminino , Humanos , Fatores Inibidores da Migração de Leucócitos/biossíntese , Leucócitos/metabolismo , Masculino , Esclerose Múltipla/sangue
2.
Ter Arkh
; 54(12): 113-7, 1982.
Artigo
em Russo
| MEDLINE
| ID: mdl-6218643