Detalhe da pesquisa
1.
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability.
EMBO Rep
; 24(12): e57234, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888778
2.
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains.
J Chem Inf Model
; 64(5): 1682-1690, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417111
3.
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface.
J Neurochem
; 152(1): 136-150, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31264722
4.
Inhibitory Properties of ATP-Competitive Coumestrol and Boldine Are Correlated to Different Modulations of CK2 Flexibility.
J Nat Prod
; 82(4): 1014-1018, 2019 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30840451
5.
Characterization of the oligomeric states of the CK2 α2ß2 holoenzyme in solution.
Biochem J
; 474(14): 2405-2416, 2017 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28572157
6.
Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking.
J Chem Inf Model
; 57(10): 2584-2597, 2017 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862840
7.
The STAS domain of mammalian SLC26A5 prestin harbours an anion-binding site.
Biochem J
; 473(4): 365-70, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26635354
8.
The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2.
Biochim Biophys Acta
; 1844(4): 722-9, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24486797
9.
Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential.
Cell Mol Life Sci
; 71(16): 3173-85, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442476
10.
Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 10): 2161-4, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100334
11.
Reevaluation of bromodomain ligands targeting BAZ2A.
Protein Sci
; 32(9): e4752, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37574751
12.
Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight.
Biochemistry
; 51(31): 6097-107, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22794353
13.
Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.
J Struct Biol
; 177(2): 382-91, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22186626
14.
Structure and single crystal spectroscopy of Green Fluorescent Proteins.
Biochim Biophys Acta
; 1814(6): 824-33, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940063
15.
The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J
; 27(13): 1907-18, 2008 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18566585
16.
Molecular architecture of the glycogen- committed PP1/PTG holoenzyme.
Nat Commun
; 13(1): 6199, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261419
17.
Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing.
ACS Med Chem Lett
; 13(9): 1434-1443, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36105334
18.
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6-Methyladenosine-Modified RNAs.
ACS Pharmacol Transl Sci
; 5(10): 872-891, 2022 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36268123
19.
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry
; 50(39): 8478-88, 2011 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21870818
20.
Structural and functional determinants of protein kinase CK2α: facts and open questions.
Mol Cell Biochem
; 356(1-2): 67-73, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739155