Detalhe da pesquisa
1.
Uncommon cytogenetic abnormalities identifying high-risk acute myeloid leukemia in children.
Future Oncol
; 16(33): 2747-2762, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32813587
2.
Insights on the Interplay between Cells Metabolism and Signaling: A Therapeutic Perspective in Pediatric Acute Leukemias.
Int J Mol Sci
; 21(17)2020 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32872391
3.
Nuclear translocation of PKC-α is associated with cell cycle arrest and erythroid differentiation in myelodysplastic syndromes (MDSs).
FASEB J
; 32(2): 681-692, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28970249
4.
Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.
J Cell Physiol
; 233(3): 1796-1811, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28777460
5.
Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting.
Biochim Biophys Acta
; 1863(3): 449-463, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334291
6.
Autophagy in acute leukemias: a double-edged sword with important therapeutic implications.
Biochim Biophys Acta
; 1853(1): 14-26, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284725
7.
Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases.
J Biol Chem
; 286(37): 31966-74, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775424
8.
Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors.
Front Oncol
; 12: 901132, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992847
9.
AICDA expression in BCR/ABL1-positive acute lymphoblastic leukaemia is associated with a peculiar gene expression profile.
Br J Haematol
; 152(6): 727-32, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21623761
10.
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP).
Blood
; 114(10): 2159-67, 2009 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19589926
11.
Philadelphia-positive acute lymphoblastic leukemia patients already harbor BCR-ABL kinase domain mutations at low levels at the time of diagnosis.
Haematologica
; 96(4): 552-7, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193419
12.
Exploiting Clonal Evolution to Improve the Diagnosis and Treatment Efficacy Prediction in Pediatric AML.
Cancers (Basel)
; 13(9)2021 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33919131
13.
The Glucocorticoid Receptor Polymorphism Landscape in Patients With Diamond Blackfan Anemia Reveals an Association Between Two Clinically Relevant Single Nucleotide Polymorphisms and Time to Diagnosis.
Front Physiol
; 12: 745032, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34721069
14.
hGATA1 Under the Control of a µLCR/ß-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1 low Mutation in Mice.
Front Genet
; 12: 720552, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34707640
15.
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance.
Blood
; 112(9): 3847-55, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18650450
16.
The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.
Haematologica
; 95(10): 1683-90, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20534699
17.
B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?
Cancers (Basel)
; 12(12)2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33255367
18.
Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of MLL-Rearrangements: A Novel Therapeutic Strategy for Pediatric AML.
Cancers (Basel)
; 12(7)2020 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698374
19.
Targeted Therapies for Pediatric AML: Gaps and Perspective.
Front Pediatr
; 7: 463, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31803695
20.
New advances in targeting aberrant signaling pathways in T-cell acute lymphoblastic leukemia.
Adv Biol Regul
; 74: 100649, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31523031