Detalhe da pesquisa
1.
Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies.
Hum Mol Genet
; 28(4): 548-560, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30329047
2.
Correction: Parkin ubiquitinates TAR-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).
J Biol Chem
; 299(1): 102828, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586191
3.
Tyrosine kinase inhibition reverses TDP-43 effects on synaptic protein expression, astrocytic function and amino acid dis-homeostasis.
J Neurochem
; 139(4): 610-623, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27507246
4.
Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice.
Hum Mol Genet
; 23(18): 4960-9, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24847002
5.
Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models.
Hum Mol Genet
; 22(16): 3315-28, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666528
6.
Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).
J Biol Chem
; 288(6): 4103-15, 2013 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23258539
7.
Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis.
J Neurochem
; 129(2): 350-61, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24298989
8.
Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.
J Biol Chem
; 287(17): 14192-200, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22378781
9.
Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5.
J Neurochem
; 118(4): 521-32, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21166806
10.
Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models.
J Neuroimmunol
; 311: 1-9, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28863860
11.
Tau deletion impairs intracellular ß-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models.
Mol Neurodegener
; 9: 46, 2014 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25384392
12.
Fractalkine signaling and Tau hyper-phosphorylation are associated with autophagic alterations in lentiviral Tau and Aß1-42 gene transfer models.
Exp Neurol
; 251: 127-38, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23333589
13.
Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance.
J Mol Med (Berl)
; 92(4): 373-86, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24337465
14.
Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-Synucleinopathy.
J Clin Cell Immunol
; 5: 259, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25635231
15.
Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance.
Autophagy
; 9(8): 1249-50, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23787811
16.
Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance.
EMBO Mol Med
; 5(8): 1247-62, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23737459
17.
Ubiquitination increases parkin activity to promote autophagic α-synuclein clearance.
PLoS One
; 8(12): e83914, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24386307
18.
Diminished parkin solubility and co-localization with intraneuronal amyloid-ß are associated with autophagic defects in Alzheimer's disease.
J Alzheimers Dis
; 33(1): 231-47, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-22954671
19.
Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1.
PLoS One
; 8(7): e69136, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23844251
20.
Fractalkine Mediates Communication between Pathogenic Proteins and Microglia: Implications of Anti-Inflammatory Treatments in Different Stages of Neurodegenerative Diseases.
Int J Alzheimers Dis
; 2012: 345472, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22919540