Detalhe da pesquisa
1.
Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Cell
; 181(3): 702-715.e20, 2020 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315619
2.
Retraction Notice to: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Cell
; 185(16): 3058, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931023
3.
Synthetic lethal targeting of TET2-mutant haematopoietic stem and progenitor cells by XPO1 inhibitors.
Br J Haematol
; 201(3): 489-501, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746437
4.
Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.
Cell
; 133(5): 864-77, 2008 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18510930
5.
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors.
Proc Natl Acad Sci U S A
; 117(28): 16516-16526, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32601179
6.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32251410
7.
Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies.
PLoS Genet
; 15(4): e1008039, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970016
8.
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
Nature
; 528(7582): 418-21, 2015 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26560027
9.
PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.
Mol Cell
; 47(5): 681-93, 2012 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22854598
10.
Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.
Blood
; 129(24): 3221-3226, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28270453
11.
Zebrafish B Cell Development without a Pre-B Cell Stage, Revealed by CD79 Fluorescence Reporter Transgenes.
J Immunol
; 199(5): 1706-1715, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739882
12.
Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.
Br J Haematol
; 177(2): 271-282, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28295194
13.
Notch signaling: switching an oncogene to a tumor suppressor.
Blood
; 123(16): 2451-9, 2014 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24608975
14.
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Blood
; 123(7): 1040-50, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24394663
15.
Malignant Peripheral Nerve Sheath Tumors.
Adv Exp Med Biol
; 916: 495-530, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165368
16.
Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia.
Br J Haematol
; 168(2): 230-8, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25256574
17.
Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.
Gastroenterology
; 147(4): 882-892.e8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24998203
18.
NOTCH and PI3K-AKT pathways intertwined.
Cancer Cell
; 12(5): 411-3, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17996644
19.
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish.
Nature
; 459(7249): 996-9, 2009 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19494811
20.
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.
Nat Rev Cancer
; 6(5): 347-59, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16612405