RESUMO
To investigate trends in travel-associated morbidity with particular emphasis on emerging infections with the potential for introduction into Europe, diagnoses of 7,408 returning travellers presenting to 16 EuroTravNet sites in 2010 were compared with 2008 and 2009. A significant increase in reported Plasmodium falciparum malaria (n=361 (6% of all travel-related morbidity) vs. n=254 (4%) and 260 (5%); p<0.001), P. vivax malaria (n=51 (1%) vs. n=31 (0.5%) and 38 (1%); p=0.027) and dengue fever (n=299 (5%) vs. n=127 (2%) and 127 (2%); p<0.001) was observed. Giardia lamblia was identified in 16% of patients with acute diarrhoea, with no significant annual variation. The proportion of acute diarrhoea due to Campylobacter increased from 7% in 2008 to 12% in 2010 (p=0.001). We recorded 121 patients with pulmonary tuberculosis in 2010, a threefold increase in the proportionate morbidity from 2008 to 2010. In 2010, 60 (0.8%) cases of chronic Chagas disease, 151 (2%) cases of schistosomiasis and 112 (2%) cases of cutaneous larva migrans were reported. Illness patterns in sentinel travellers, captured by EuroTravnet, continue to highlight the potential role of travellers in the emergence of infectious diseases of public health concern in Europe and the relevance of offering medical travel advice and enforcing specific and adequate prophylaxis.
Assuntos
Doenças Transmissíveis/epidemiologia , Migrantes/estatística & dados numéricos , Viagem/estatística & dados numéricos , Adulto , Doenças Transmissíveis/diagnóstico , Doenças Transmissíveis/etiologia , Dengue/epidemiologia , Diarreia/epidemiologia , Europa (Continente)/epidemiologia , Feminino , Gastroenteropatias/epidemiologia , Humanos , Malária/epidemiologia , Masculino , Pessoa de Meia-Idade , Morbidade , Vigilância da População , Infecções Respiratórias/epidemiologia , Dermatopatias/epidemiologiaRESUMO
This article provides a brief overview of some diseases transmitted by ticks. These vectors do not transmit only Lyme disease and tickborne-encephalitis, even in Switzerland. Several tick-borne diseases cause nonspecific flu-like symptoms. Nevertheless sometimes severe, some of these diseases can be treated with specific treatments. Repellents, appropriate clothes impregnated with permethrine and prompt removal of the tick are effective preventive measures to limit the risk of infection. There is an effective vaccine which protects against tick-borne encephalitis.
Assuntos
Vetores Aracnídeos , Mordeduras e Picadas , Carrapatos/microbiologia , Carrapatos/virologia , Animais , Infecções por Borrelia/prevenção & controle , Infecções por Borrelia/transmissão , Vírus da Febre Hemorrágica da Crimeia-Congo , Febre Hemorrágica da Crimeia/prevenção & controle , Febre Hemorrágica da Crimeia/transmissão , Humanos , Infecções por Rickettsia/prevenção & controle , Infecções por Rickettsia/transmissãoRESUMO
Respiratory tract infections are a frequent cause of travelers' health problems. Tropical diseases are relatively rare compared to common respiratory infections. Nevertheless, due to their potential gravity, they must be systematically considered. The differential diagnosis of tropical pathogens is wide. A targeted travel history taking into account specific epidemiological, geographical and behavioral risk factors helps focusing biological exams to identify the causative diagnosis. The chest radiography remains very helpful in this context; however, more specific exams, such as serologies are often necessary to reach a final diagnosis.
Assuntos
Doenças Respiratórias/diagnóstico , Doenças Respiratórias/etiologia , Viagem , Humanos , Doenças Respiratórias/epidemiologiaRESUMO
Rickettsial diseases are arthropod-borne zoonosis. They are still misdiagnosed in Switzerland. Since development in molecular genetics, number of pathogenic species increased dramatically. In recent years, the incidence rise worldwide. Climatic conditions and development of tropical travels could explain it. In a near future, the Swiss general practitioner may face an increase of cases. Clinical presentation is unspecified. The eschar is the key diagnostic element but can be easily overlooked. Serology, the indirect immunofluorescence assay is the reference method. PCR can give the diagnosis in acute phase. However empirical treatment should be prescribed as soon as diagnosis is suspected. No vaccine is currently available and use of repellent is still the best way of prevention.
Assuntos
Infecções por Rickettsiaceae/diagnóstico , Infecções por Rickettsiaceae/epidemiologia , Animais , Antibacterianos/uso terapêutico , Vetores Aracnídeos , Mordeduras e Picadas , Humanos , Infecções por Rickettsiaceae/tratamento farmacológico , Infecções por Rickettsiaceae/transmissão , Suíça/epidemiologia , Carrapatos/microbiologiaRESUMO
We report the fatal case of acute melioidosis in a patient returning from Martinique with fever in November 2010. Gram-negative rods were isolated from a blood culture and Burkholderia pseudomallei identified within 24 hours after first medical contact. The patient died two days after admission to hospital despite intravenous therapy with high doses of imipenem/cilastatin and intensive care. Clinicians seeing travellers returning from the subtropics or tropics with severe pneumonia or septicaemia should consider the possibility of acute melioidosis.
Assuntos
Burkholderia pseudomallei/isolamento & purificação , Melioidose/diagnóstico , Viagem , Abscesso/diagnóstico , Abscesso/tratamento farmacológico , Abscesso/etiologia , Adulto , Antibacterianos/uso terapêutico , Burkholderia pseudomallei/genética , Evolução Fatal , Febre/etiologia , Geografia , Humanos , Imipenem/uso terapêutico , Masculino , Martinica , Espectrometria de Massas , Melioidose/tratamento farmacológico , Melioidose/microbiologia , Pessoa de Meia-Idade , Análise de Sequência de DNA , SuíçaRESUMO
A 35 year-old man was admitted to the hospital for fever upon returning from the Caribbean area. He died 48 hours later, after developing pulmonary lesions that were complicated by multi-organ failure, despite rapid diagnosis of melioidosis by mass spectrometry on blood cultures. Melioidosis is a rare bacterial disease in the traveller that is caused by Burkholderia pseudomallei. Although the clinical presentation is variable, pneumonia is the most frequent finding. Diagnosis may be considered in travellers returning from tropical and subtropical regions, especially during rainy seasons. Accordingly, when confronted with a patient who presents with fever after travelling, it is important to carefully specify the regions visited, potential expositions, and rapidly offer adequate laboratory testing.
Assuntos
Melioidose/diagnóstico , Viagem , Clima Tropical , Adulto , Antibacterianos/uso terapêutico , Febre/microbiologia , Humanos , Masculino , Melioidose/tratamento farmacológico , Melioidose/epidemiologiaRESUMO
The importance of Japanese encephalitis (JE) in endemic populations and in travellers requires a balanced assessment. This disease represents an important public health problem in some endemic areas, which contrasts with the minimal risk for travellers to endemic areas. This is reflected by high numbers of infections mainly among children in endemic countries and by few case reports among tourists and even expatriates. The total number of case reports between 1978 and 2008 amounts to a risk of one to two cases per year. Nevertheless, some travelling groups may be at higher risk when visiting or working in high risk areas. A new vaccine against Japanese encephalitis will soon be registered in Switzerland. This paper contributes to the scarce data available for decision making whether or not to recommend the vaccination to tourists and expatriates.
Assuntos
Encefalite Japonesa/epidemiologia , Encefalite Japonesa/prevenção & controle , Encefalite Japonesa/transmissão , Doenças Endêmicas , Humanos , Risco , ViagemRESUMO
Physicians in Europe are likely to see more African trypanosomiasis cases because of the increasing popularity of travel to Africa. In this paper the literature on imported cases in Europe, since 2005 is reviewed. Because of the high mortality risk associated with acute Rhodesian trypanosomiasis, travellers should be informed about preventive measures and the early disease manifestations.
Assuntos
Surtos de Doenças/estatística & dados numéricos , Emigração e Imigração/estatística & dados numéricos , Tripanossomíase Africana/epidemiologia , África/epidemiologia , Europa (Continente)/epidemiologia , Humanos , Incidência , Vigilância da População , Medição de Risco/métodos , Fatores de RiscoRESUMO
Frequently, expatriates and humanitarian workers change their lifestyle during expatriation and take more risks. Exposure to sun and heat, alcohol abuse, unprotected sexual relationships, stress, accidents and security incidents are the main non infectious health risks. It is important to prevent them, as the consequences are more serious abroad. Their prevention lies on the responsibility of every individual to adapt their behaviour and lifestyle to the environment, as well as on institutional guidelines concerning risky behaviour.
Assuntos
Alcoolismo/prevenção & controle , Altruísmo , Desidratação/prevenção & controle , Golpe de Calor/prevenção & controle , Segurança , Viagem , Violência , Agressão , Humanos , Fatores de RiscoRESUMO
Hijacking, crime, aggression and theaft when people travel abroad are regularly reported by the media. This increases travellers' fears. As there is little research that quantifies risks, subjectivity and preconceived ideas prevail. A survey done among travellers in Geneva, Lausanne and Lyon showed that the risk of incidents was lower in countries located outside of Europe, usually in cities. Most frequently it was baggage stealing, or stealing in the street, during the day. In Europe, stealing by breaking into cars was most frequent. Without becoming paranoid about aggression and burglary, some simple rules can be followed. Keep constant situational awareness, be respectful of the people in countries visited, avoid provocative attitudes and avoid insecure areas.
Assuntos
Crime/prevenção & controle , Crime/estatística & dados numéricos , Segurança , Viagem , HumanosRESUMO
To be an expatriate can be a very rewarding experience. Nevertheless, it requires a great ability of adaptation to a new environment. The living and professional conditions may be very demanding. They can have an influence on the physical and mental health. The basic and cumulative stress should be prevented by a good preparation before departure, a thorough follow-up during the expatriation and upon return. The expatriate, the family doctor and the employer play an important role during the whole period of expatriation. Their close collaboration permits an ideal management of possible stress related problems.
Assuntos
Emigrantes e Imigrantes/psicologia , Saúde Mental , Estresse Psicológico/prevenção & controle , HumanosRESUMO
Travellers' diarrhoea represents the most frequent health problem when travelling in developing countries. In most cases it is a self-limited disease. Nonetheless it can cause incapacitation and significant morbidity. It can become persistent in up to 3% of travellers who have suffered from acute diarrhoea in regions at high risk. This article discusses the investigations and the management of diarrhoea in returning travellers, preventive measures and its management during travel.
Assuntos
Diarreia/prevenção & controle , Viagem , Antibacterianos/uso terapêutico , Antidiarreicos/uso terapêutico , Países em Desenvolvimento , Diarreia/epidemiologia , Diarreia/terapia , Hidratação , Motilidade Gastrointestinal , HumanosRESUMO
Japanese encephalitis is the primary cause of viral encephalitis in Asia where it is annually responsible for the death of around 20,000 people. The virus is transmitted by night-biting mosquitoes in wet rural areas. The classical clinical presentation includes fever, paresis, decreased level of consciousness and convulsions. There is no efficient anti-viral treatment available. Avoidance of mosquito bites and vaccination are the only effective measures to prevent the disease. Vaccination is recommended for travellers and expatriates who will stay in rural endemic areas for at least one month during the rainy season. The vaccine is contra-indicated in individuals with a previous history of severe allergic reaction.
Assuntos
Encefalite Japonesa/epidemiologia , Encefalite Japonesa/prevenção & controle , Encefalite Japonesa/diagnóstico , Doenças Endêmicas , Humanos , Vacinas contra Encefalite JaponesaRESUMO
Intestinal parasites represent an important burden of disease mainly in developing countries. Physicians practicing in Europe can be exposed to these diseases, mainly seen in immigrants or travellers returning from tropical countries. Several parasitic diseases remain ubiquitous and can be contracted in developed countries. Most often, parasitic infections cause no or only few symptoms, but some can lead to serious disease in immuno-compromised patients. Diagnostic procedures and treatments available are discussed.
Assuntos
Enteropatias Parasitárias/diagnóstico , Enteropatias Parasitárias/tratamento farmacológico , Hepatopatias Parasitárias/diagnóstico , Hepatopatias Parasitárias/tratamento farmacológico , Animais , Anti-Helmínticos/uso terapêutico , Antiprotozoários/uso terapêutico , HumanosRESUMO
Despite a spectacular increase of international travels, related psychiatric problems remain understudied. Travelling is a stressing factor that may trigger or aggravate mood disorders, anxiety disorders or substance related problems. Expatriates are especially at elevated risk for adaptation problems due to the length of their stays abroad. Some destinations with strong symbolic or mystical connotations are associated with acute psychotic episodes. Anticipating changes and being prepared to face new solicitations to come allows to reduce risks for mental health while travelling.
Assuntos
Transtornos Mentais/psicologia , Viagem/psicologia , Humanos , Transtornos Mentais/etiologia , Estresse Psicológico/psicologiaRESUMO
The consumption of dishes made from raw fresh- or see-water fishes exposes many individuals (residents, visitors or migrants) from tropical to arctic regions to the risk of helminthiasis. Anisakiasis, diphyllobothriasis, clonorchiasis, opistorchiasis and gnathostomiasis have distinct parasitic cycles and various clinical presentations, from sub-clinical infections to life-threatening hemorragic or tumoral complications. In-depth history, clinical presentation, stool examination for ova and parasites and serology usually allow for a specific diagnosis to be made. The common anti-parasitic drugs, such as albendazole, ivermectin and praziquantel, are efficacious against most of these helminthiasis. Sufficient cooking or freezing of fishes before consumption are very efficient preventive measures.
Assuntos
Peixes/parasitologia , Helmintíase/transmissão , Animais , Parasitologia de Alimentos , Helmintíase/diagnóstico , Helmintíase/tratamento farmacológico , HumanosRESUMO
Epidemiological surveillance of malaria cases reported in Geneva between 1998 and 2004 is analysed and compared to a similar retrospective study conducted in 1988-1994. A total of 426 cases have been reported, with a mean of 61 cases per year and an increase of 29,4% compared to the initial study. Most of the increase was seen in patients of African origin, from 115 to 170 cases, of whom 56% visited friends and relatives. Malaria was acquired predominantly in sub-Saharan Africa (88,5%), mainly West and Central Africa. P. falciparum was the predominant species (75,3%), with significant seasonality during the summer and in January. This was not the case for other species. Two third of cases did not take any chemoprophylaxis. These results stress the importance of the disease and the need for adequate protection of travellers.